Technology Process of N-beta-alanyl-L-histidine
There total 40 articles about N-beta-alanyl-L-histidine which
guide to synthetic route it.
The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:
synthetic route:
- Guidance literature:
-
With
ammonium bicarbonate;
at 60 ℃;
for 24h;
- Guidance literature:
-
With
5%-palladium/activated carbon; hydrogen;
In
methanol; water;
for 24h;
under 760.051 Torr;
- Guidance literature:
-
N-9-fluorenylmethyloxycarbonyl-N-trityl-L-histidine;
With
trityl chloride polystyrene resin; N-ethyl-N,N-diisopropylamine;
In
dichloromethane; N,N-dimethyl-formamide;
for 0.5h;
trityl chloride resin
With
piperazine;
In
dichloromethane; N,N-dimethyl-formamide;
for 1h;
trityl chloride resin
Inert atmosphere;
3-(tert-butyloxycarbonylamino)propionic acid;
Further stages;
DOI:10.5935/0103-5053.20160064