(S)(+)-2-AMINOPENTANE-HCL

Base Information

• Chemical Name: (S)(+)-2-AMINOPENTANE-HCL
• CAS No.: 54542-13-1
• Molecular Formula: C5H13N
• Molecular Weight: 87.1649
• Hs Code.: 2921199090
• Mol file: 54542-13-1.mol

Synonyms:(S)(+)-2-AMINOPENTANE-HCL;(S)-Pentan-2-amine

Chemical Property of (S)(+)-2-AMINOPENTANE-HCL

Chemical Property:

• PSA: 26.02000
• LogP: 1.83400

Purity/Quality:

99%min ^*data from raw suppliers

(2S)-2-Pentanamine ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

• Uses: (2S)-2-Pentanamine is a chiral reagent used in the study of identification of enantioselective extractants for chiral separation of amines and aminoalcohols.

Technology Process of (S)(+)-2-AMINOPENTANE-HCL

There total 38 articles about (S)(+)-2-AMINOPENTANE-HCL which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 99.8%

3-phenoxy-2-propanone (621-87-4) + 2-Pentanone (107-87-9) → (R)‐2‐aminopentane (625-30-9,33985-20-5,54542-13-1,63493-28-7) + R-(-)-1-phenoxy-2-propanamine (45972-74-5)

Guidance literature:

With Candida boidinii formate dehydrogenase; pyridoxal 5'-phosphate; Aspergillus terreus ω-trans aminase; Lysinibacillus fusiformis leucine dehydrogenase; ammonium formate; nicotinamide adenine dinucleotide; In aq. buffer; at 30 ℃; for 24h; pH=8.8; Catalytic behavior; Green chemistry; Enzymatic reaction;

DOI:10.1021/acs.joc.9b02445

Reference yield: 99.4%

4-methoxybenzyl methyl ketone (122-84-9) + 2-Pentanone (107-87-9) → (R)‐2‐aminopentane (625-30-9,33985-20-5,54542-13-1,63493-28-7) + (R)-(-)-p-methoxyamphetamine (58993-79-6,23239-32-9)

Guidance literature:

With Candida boidinii formate dehydrogenase; pyridoxal 5'-phosphate; Aspergillus terreus ω-trans aminase; Lysinibacillus fusiformis leucine dehydrogenase; ammonium formate; nicotinamide adenine dinucleotide; In aq. buffer; at 30 ℃; for 24h; pH=8.8; Catalytic behavior; Green chemistry; Enzymatic reaction;

DOI:10.1021/acs.joc.9b02445

Reference yield: 99.4%

4-fluorophenyl acetone (459-03-0) + 2-Pentanone (107-87-9) → (R)‐2‐aminopentane (625-30-9,33985-20-5,54542-13-1,63493-28-7) + (R)-(-)-α-methyl-β-(4-fluorophenyl)ethylamine (72522-20-4)

Guidance literature:

With Candida boidinii formate dehydrogenase; pyridoxal 5'-phosphate; Aspergillus terreus ω-trans aminase; Lysinibacillus fusiformis leucine dehydrogenase; ammonium formate; nicotinamide adenine dinucleotide; In aq. buffer; at 30 ℃; for 24h; pH=8.8; Catalytic behavior; Green chemistry; Enzymatic reaction;

DOI:10.1021/acs.joc.9b02445

upstream raw materials:

2-pentylamine

(4R,1'R)-3-(1'-methylbutyl)-4-phenyloxazolidin-2-one

3-nitro-pentan-2-ol

(E)-3-nitro-2-pentene

Downstream raw materials:

(1R)-N-(1-Methylbutyl)-4-methoxibenzamid

Refernces

• 1、 Tseliou, Vasilis,Schilder, Don,Masman, Marcelo F.,Knaus, Tanja,Mutti, Francesco G.. "Generation of Oxidoreductases with Dual Alcohol Dehydrogenase and Amine Dehydrogenase Activity". supporting information. p. 3315 - 3325. Retrieved 2020/12/11.
• 2、 Li, Jianjiong,Wang, Yingang,Wu, Qiaqing,Yao, Peiyuan,Yu, Shanshan,Zhu, Dunming. "Simultaneous Preparation of (S)-2-Aminobutane and d -Alanine or d -Homoalanine via Biocatalytic Transamination at High Substrate Concentration". supporting information. . Retrieved 2022/03/01.