Benzeneethanethioic acid, S-phenyl ester

Base Information

• Chemical Name: Benzeneethanethioic acid, S-phenyl ester
• CAS No.: 18245-74-4
• Molecular Formula: C14H12OS
• Molecular Weight: 228.315
• Mol file: 18245-74-4.mol

Synonyms:

Chemical Property of Benzeneethanethioic acid, S-phenyl ester

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of Benzeneethanethioic acid, S-phenyl ester

There total 29 articles about Benzeneethanethioic acid, S-phenyl ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 100.0%

thiophenol (108-98-5) + 3-Phenylacetyl-thiazolidin-(2Z)-ylidene-cyanamide → S-phenyl 2-phenylethanethioate (18245-74-4)

Guidance literature:

With sodium ethanolate; In ethanol; at 60 ℃; for 0.5h;

DOI:10.3987/COM-87-4377

Reference yield: 99.0%

phenylacetic acid (103-82-2) + thiophenol (108-98-5) → S-phenyl 2-phenylethanethioate (18245-74-4)

Guidance literature:

With trifluoroacetic acid; In acetonitrile; at 60 ℃; for 2h;

DOI:10.1080/10426507.2012.664220

Reference yield: 99.0%

(phenylsulfenyl)zinc bromide (1449477-04-6) + phenylacetyl chloride (103-80-0) → S-phenyl 2-phenylethanethioate (18245-74-4)

Guidance literature:

In neat (no solvent); at 23 ℃; for 0.0833333h;

DOI:10.1002/ejoc.201600366

upstream raw materials:

thiophenol

phenylacetyl chloride

N-nitroso-p-methyl-acetanilide

phenyl phenyldithioacetate

Downstream raw materials:

diphenyl sulfide

thiophenol

1,1'-(1,2-ethanediyl)bisbenzene

toluene

Refernces

• 1、 Wang, Wei,Qi, Xinxin,Wu, Xiao-Feng. "Palladium-Catalyzed Thiocarbonylation of Benzyl Chlorides with Sulfonyl Chlorides for the Synthesis of Arylacetyl Thioesters". supporting information. p. 2541 - 2545. Retrieved 2021/03/16.
• 2、 Dall'Oglio, Evandro L.,Stein, André L.,Vasconcelos, Leonardo G.,Vieira, Lucas C. C.,de Oliveira, Angélica J.,de Oliveira, Sandynara A.. "Synthesis of selenol esters via the reaction of acyl chlorides with diselenides in the presence of Zn dust catalyzed by CoCl2·6H2O". supporting information. . Retrieved 2021/08/25.