1041434-07-4

Basic information

• Product Name: 1-bromo-3,5-bis(2-hydroxyethoxy)benzene
• Synonyms: 1-bromo-3,5-bis(2-hydroxyethoxy)benzene
• CAS NO: 1041434-07-4
• Molecular Weight: 277.115
• Mol File: 1041434-07-4.mol
• Article Data: 3

Chemical Properties

• CAS DataBase Reference: 1-bromo-3,5-bis(2-hydroxyethoxy)benzene(CAS DataBase Reference)
• NIST Chemistry Reference: 1-bromo-3,5-bis(2-hydroxyethoxy)benzene(1041434-07-4)
• EPA Substance Registry System: 1-bromo-3,5-bis(2-hydroxyethoxy)benzene(1041434-07-4)

Safety Data

• Hazardous Substances Data: 1041434-07-4(Hazardous Substances Data)

Upstream product

• 96-49-1 [1,3]-dioxolan-2-one 
• 106120-04-1 5-bromoresorcinol 

Downstream Products

• 1041434-08-5 1-bromo-3,5-bis[2-(tert-butyldimethylsilyloxy)ethoxy]benzene 

Relevant articles and documents

Polymerisable compounds and the use thereof in liquid-crystal displays

The present invention relates to polymerizable compounds, to processes and intermediates for the preparation thereof, to liquid-crystal (LC) media comprising them, and to the use of the polymerizable compounds and LC media for optical, electro-optical and

Tailoring a bacteriochlorin building block with cationic, amphipathic, or lipophilic substituents

(Chemical Equation Presented) Bacteriochlorins are attractive candidates for photodynamic therapy (PDT) of diverse medical indications owing to their strong absorption in the near-infrared (NIR) region, but their use has been stymied by lack of access to stable, synthetically malleable molecules. To overcome these limitations, a synthetic free base 3,13-dibromobacteriochlorin (BC-Br3Br13) has been exploited as a building block in the synthesis of diverse bacteriochlorins via Pd-mediated coupling reactions (Sonogashira, Suzuki, and reductive carbonylation). Each bacteriochlorin is stable to adventitious dehydrogenation by virtue of the presence of a geminal dimethyl group in each pyrroline ring. The target bacteriochlorins bear cationic, lipophilic, or amphipathic substituents at the 3- and 13- (β-pyrrolic) positions. A dicarboxybacteriochlorin was converted to amide derivatives via the intermediate diacid chloride. A diformylbacteriochlorin was subjected to reductive amination to give aminomethyl derivatives. A set of 3,5-disubstituted aryl groups bearing lipophilic or amphipathic groups was introduced via Suzuki coupling. Altogether 22 free base bacteriochlorins have been prepared. Eight aminoalkylbacteriochlorins were quaternized with methyl iodide at two or four amine sites per molecule, which resulted in water solubility. Each bacteriochlorin exhibits a Qy absorption band in the range of 720-772 nm. The ability to introduce a wide variety of peripheral functional groups makes these bacteriochlorins attractive candidates for diverse applications in photomedicine including PDT in the NIR region.