108393-28-8Relevant articles and documents
A cross metathesis approach to the synthesis of the C11-C23 fragment of (-)-16-normethyldictyostatin
Sai Baba,Das, Parthasarathi,Mukkanti,Iqbal, Javed
, p. 7927 - 7930 (2007/10/03)
The synthesis of the C11-C23 fragment 2 of (-)-16-normethyldictyostatin has been achieved by cross metathesis between two olefinic fragments 4 and 5 followed by a reduction of the double bond at C16-C17. Both the olefinic fragments are easily synthesized
Stereoselection at the Steady State in Radical Cyclizations of Acyclic Systems Containing One Radical Acceptor and Two Precursors in a 1,5- Relationship under Pseudo-First-Order Conditions
Andrukiewicz, Robert,Cmoch, Piotr,Gawel, Anna,Stalinski, Krzysztof
, p. 1844 - 1848 (2007/10/03)
The first example of a successive kinetic resolution of acyclic diastereomeric radical intermediates in a 1,5-relationship under pseudo-first-order conditions is reported. A mechanistic model involves nonselective generation of the radical intermediates followed by different partitioning of these between two different chemical pathways. The "2,5-cis" selectivity in the radical cyclization step arises from transition geometries with the substituents aligned in pseudoequatorial positions.
Synthesis of stereotriads by oxymercuration of substituted cyclopropylcarbinols.
Cossy,Blanchard,Meyer
, p. 2567 - 2569 (2007/10/03)
[structure: see text] Cyclopropylcarbinol derivatives bearing an adjacent methyl-substituted stereocenter and a remote beta-hydroxy group protected as a pivalate underwent anchimerically assisted regio- and diastereoselective oxymercurations, affording af
