119347-14-7Relevant articles and documents
Synthesis and biological evaluation of new taxoids derived from 2-deacetoxytaxinine J
Botta, Maurizio,Armaroli, Silvia,Castagnolo, Daniele,Fontana, Gabriele,Pera, Paula,Bombardelli, Ezio
, p. 1579 - 1583 (2007/10/03)
A small library of 2-deacetoxytaxinine J (DAT-J) 1 derivatives was synthesised and tested in vitro for their reversal activity in human mammary carcinoma MDR cell line MCF7-R. One of the new taxoids showed to be active at 0.1 μM when tested in combination
Synthesis of azetidine-type taxanes
Fenoglio,Nano,Vander Velde,Appendino
, p. 3203 - 3206 (2007/10/03)
Starting from the alkaloid 2'-deacetoxyaustrospicatine (2) azetidine isosteres of the oxetane-type laxane 1-deoxy-2-debenzoyloxy-4-deacetylbaccatin VI were synthesized.
PLANTES DE NOUVELLE-CALEDONIE. 114. TAXANES ISOLES DES FEUILLES D'AUSTROTAXUS SPICATA COMPTON (TAXACEES)
Ettouati, Laurent,Ahond, Alain,Convert, Odile,Laurent, Dominique,Poupat, Christiane,Potier, Pierre
, p. 749 - 755 (2007/10/02)
Seventeen compounds have been isolated from the leaves of Austrotaxus spicata: anemonine, usually extracted only from Renonculaceae, is the main product; the other have a taxane skeleton.Fourteen are alkaloidal and new; among these, twelve are described h