125464-42-8 Usage
Description
SACLOFEN, also known as 4-chloro-N-[(1,1-dimethylethyl)sulfonyl]-N-(4-fluorophenyl)benzamide, is a potent and selective GABAB receptor antagonist. It has been found to exhibit various pharmacological properties, making it a promising candidate for a range of applications in different industries.
Uses
Used in Pharmaceutical Industry:
SACLOFEN is used as a GABAB receptor antagonist for reducing leukocyte migration and increasing Fos expression in T7-T11 sympathetic preganglionic neurons. This application is particularly relevant in the development of treatments for conditions involving inflammation and immune system dysregulation.
Used in Pain Management Research:
In the field of pain management, SACLOFEN is used as a GABAB receptor antagonist to study the analgesic effect of repeated injections of oxycodone in rats. This application aids in understanding the underlying mechanisms of pain relief and the potential for developing more effective pain management strategies.
Biochem/physiol Actions
Saclofen might possess sympathetic nervous system-dependent anti-inflammatory action.
Check Digit Verification of cas no
The CAS Registry Mumber 125464-42-8 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,2,5,4,6 and 4 respectively; the second part has 2 digits, 4 and 2 respectively.
Calculate Digit Verification of CAS Registry Number 125464-42:
(8*1)+(7*2)+(6*5)+(5*4)+(4*6)+(3*4)+(2*4)+(1*2)=118
118 % 10 = 8
So 125464-42-8 is a valid CAS Registry Number.
InChI:InChI=1/C9H12ClNO3S/c10-9-3-1-7(2-4-9)8(5-11)6-15(12,13)14/h1-4,8H,5-6,11H2,(H,12,13,14)
