126737-42-6

Basic information

• Product Name: Acetylsventenic acid
• Synonyms: Acetylsventenic acid;(4beta,7beta)-7-(Acetyloxy)-kaur-16-en-18-oic acid
• CAS NO: 126737-42-6
• Molecular Formula: C22H32O4
• Molecular Weight: 360.48708
• Mol File: 126737-42-6.mol
• Article Data: 3

Chemical Properties

• Boiling Point: 475.1±45.0 °C(Predicted)
• Appearance: /
• Density: 1.15±0.1 g/cm3(Predicted)
• PKA: 4.55±0.60(Predicted)
• CAS DataBase Reference: Acetylsventenic acid(CAS DataBase Reference)
• NIST Chemistry Reference: Acetylsventenic acid(126737-42-6)
• EPA Substance Registry System: Acetylsventenic acid(126737-42-6)

Safety Data

• Hazardous Substances Data: 126737-42-6(Hazardous Substances Data)

Usage

General Description

Acetylsalicylic acid, commonly known as aspirin, is a synthetic compound derived from salicylic acid. It is a key ingredient in many over-the-counter pain relievers and fever reducers. Acetylsalicylic acid works by inhibiting the production of prostaglandins, which are chemicals in the body that cause inflammation and pain. It is also a blood thinner, which can help prevent blood clots that can lead to heart attacks and strokes. In addition to its medicinal properties, acetylsalicylic acid is also used in the production of dyes, fragrances, and plastics. While generally considered safe for most people, it can cause stomach irritation and is not recommended for individuals with certain health conditions or allergies.

Upstream product

• 43161-43-9 7β-acetoxy-18-hydroxy-ent-kaur-16-ene 
• 43161-40-6 7β-acetoxy-ent-kaur-16-ene 
• 21435-01-8 7β-hydroxy-(-)-kaur-16-en-19-oic acid 
• 108-24-7 acetic anhydride 
• 43161-43-9 Epicandicandiol 7β-monoacetate 

Downstream Products

• 18493-13-5 Sventenic acid 

Relevant articles and documents

Biotransformation of ent-kaur-16-ene and ent-trachylobane 7β-acetoxy derivatives by the fungus Gibberella fujikuroi (Fusarium fujikuroi)

Candol A (7β-hydroxy-ent-kaur-16-ene) (6) is efficiently transformed by Gibberella fujikuroi into the gibberellin plant hormones. In this work, the biotransformation of its acetate by this fungus has led to the formation of 7β-acetoxy-ent-kaur-16-en-19-oic acid (3), whose corresponding alcohol is a short-lived intermediate in the biosynthesis of gibberellins and seco-ring ent-kaurenoids in this fungus. Further biotransformation of this compound led to the hydroxylation of the 3β-positions to give 7β-acetoxy-3β- hydroxy-ent-kaur-16-en-19-oic acid (14), followed by a 2β- or 18-hydroxylation of this metabolite. The incubation of epicandicandiol 7β-monoacetate (7β-acetoxy-18-hydroxy-ent-kaur-16-ene) (10) produces also the 19-hydroxylation to form the 18,19 diol (20), which is oxidized to give the corresponding C-18 or C-19 acids. These results indicated that the presence of a 7β-acetoxy group does not inhibit the fungal oxidation of C-19 in 7β-acetoxy-ent-kaur-16-ene, but avoids the ring B contraction that leads to the gibberellins and the 6β-hydroxylation necessary for the formation of seco-ring B ent-kaurenoids. The biotransformation of 7β-acetoxy-ent- trachylobane (trachinol acetate) (27) only led to the formation of 7β-acetoxy-18-hydroxy-ent-trachylobane (33).

Didymooblongin, a New Kaurenoid Diterpene from Didymocarpus oblonga Wall.

Didymooblongin (III), a new kaurenoid diterpene isolated from the whole plant of Didymocarpus oblonga, has been formulated as 7β-hydroxy-(-)-16-kaurene-19-oic acid (III) on the basis of spectral and chemical evidences.