129952-14-3Relevant articles and documents
Synthesis and biological evaluation of paleo-soraphens
Lu, Hai-Hua,Raja, Aruna,Franke, Raimo,Landsberg, Dirk,Sasse, Florenz,Kalesse, Markus
supporting information, p. 13549 - 13552 (2014/01/06)
Synthesis can provide molecules such as paleo-soraphens A and B (see scheme) that are genetically encoded but not obtained from the natural source. Although it is unclear whether this is part of an evolutionary process or the consequence of the chemical synthesis, the biological evaluation of these genetically encoded natural products can shed light on how natural products are structurally optimized with respect to their biological profile. Copyright
Total Synthesis of (+)-Carbonolide B
Keck, Gary E.,Palani, Anandan,McHardy, Stanton F.
, p. 3113 - 3122 (2007/10/02)
The macrolide (+)-carbonolide B, the aglycon of the antibiotic carbomycin B, was synthesized via a convergent sequence.A key step of the approach is the union of aldehyde 6 with stannane 7 in the presence of MgBr2*OEt2 as Lewis acid to afford the C1-C9 fr
Synthesis of the cyclohexyl fragment of FK-506 by intramolecular ene-reaction
Maier,Schoffling
, p. 3007 - 3010 (2007/10/02)
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