132234-69-6 Usage
General Description
Endo-3-Boc-aminotropane, also known as tropinone, is a chemical compound that is used as a precursor in the synthesis of a variety of pharmaceuticals and psychoactive substances. It is a tropane alkaloid that is structurally similar to cocaine, and has stimulant and hallucinogenic properties. The "endo-3-Boc" in its name refers to the placement of a tert-butoxycarbonyl (Boc) group on the nitrogen atom, which is often used as a protective group in organic synthesis. Aminotropane compounds have been studied for their potential therapeutic effects in treating neurological disorders and substance abuse, as well as in the development of new psychoactive substances. However, they also have a high potential for abuse and are controlled substances in many countries.
Check Digit Verification of cas no
The CAS Registry Mumber 132234-69-6 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,3,2,2,3 and 4 respectively; the second part has 2 digits, 6 and 9 respectively.
Calculate Digit Verification of CAS Registry Number 132234-69:
(8*1)+(7*3)+(6*2)+(5*2)+(4*3)+(3*4)+(2*6)+(1*9)=96
96 % 10 = 6
So 132234-69-6 is a valid CAS Registry Number.
InChI:InChI=1/C13H24N2O2/c1-13(2,3)17-12(16)14-9-7-10-5-6-11(8-9)15(10)4/h9-11H,5-8H2,1-4H3,(H,14,16)/t9-,10+,11-
132234-69-6Relevant articles and documents
Quinolone Antibacterials: Preparation and Activity of Bridged Bicyclic Analogues of the C7-Piperazine
Kiely, John S.,Hutt, Marland P.,Culbertson, Townley P.,Bucsh, Ruth A.,Worth, Donald F.,et al.
, p. 656 - 663 (2007/10/02)
A series of quinolone and naphthyridine antibacterial agents possessing as the C7-heterocycle bicyclic 2,5-diazabicycloalkanes, where n = 2, 3 and m = 1, 2, and a series including 4-aminopiperidine and 3-amino-8-azabicyclooctanes have been prepared and evaluated in vitro and in vivo for antibacterial activity against a variety of Gramm-negative and Gramm-positive organisms.These compounds were also tested against the target enzyme bacterial DNA gyrase.All the examples investigated are nearly equipotent with the parent 7-piperazinyl analogues.Only endo-7-(3-amino-8-azabicyclooct-8-yl) -1-cyclopropyl-6,8-difluoro-1,4-dihydro-4-oxo-3-quinolinecarboxylic acid displays activity that surpasses that of the piperazine parent.