132294-14-5Relevant articles and documents
CYCLOBUTYL NUCLEOSIDE ANALOGS AS ANTI-VIRALS
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Paragraph 0250; 0286, (2020/07/07)
Described herein are cyclobutyl nucleoside analogs of Formula (I), pharmaceutical compositions that include one or more cyclobutyl nucleoside analogs and methods of using the same to treat HBV, HDV and/or HIV.
Synthesis and antiviral activity of enantiomeric forms of cyclobutyl nucleoside analogues
Bisacchi,Braitman,Cianci,Clark,Field,Hagen,Hockstein,Malley,Mitt,Slusarchyk,Sundeen,Terry,Tuomari,Weaver,Young,Zahler
, p. 1415 - 1421 (2007/10/02)
The syntheses of the enantiomeric cyclobutyl guanine nucleoside analogues [1R-1α,2β,3α]- and [1S-1α,2β,3α]-2-amino-9-[2,3-bis(hydroxymethyl) cyclobutyl]-6H-purin-6-one (7 and 8, respectively) and the enantiomeric cyclobutyl adenine analogues [1R-1α,2β,3α]