1609377-82-3

Basic information

• Product Name: C₁₈H₂₇ClN₂O₄
• CAS NO: 1609377-82-3
• Molecular Weight: 370.876
• Mol File: 1609377-82-3.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: C₁₈H₂₇ClN₂O₄(CAS DataBase Reference)
• NIST Chemistry Reference: C₁₈H₂₇ClN₂O₄(1609377-82-3)
• EPA Substance Registry System: C₁₈H₂₇ClN₂O₄(1609377-82-3)

Safety Data

• Hazardous Substances Data: 1609377-82-3(Hazardous Substances Data)

Upstream product

• 1271175-95-1 2,6-dinitro-4-n-dodecylphenol 
• 104-43-8 4-dodecylphenol 

Downstream Products

• 1609377-83-4 C₁₈H₂₇FN₂O₄ 
• 1271176-06-7 C₁₈H₃₁FN₂ 
• 1609377-84-5 C₃₂H₃₈F₃N₃O₂ 
• 1609377-85-6 C₄₁H₄₃F₄N₃O₅ 
• 1609377-86-7 C₄₀H₄₁F₄N₃O₅ 
• 1609377-87-8 C₄₀H₄₀ClF₄N₃O₄ 
• 1609377-89-0 C₇₀H₈₂F₅N₉O₆ 
• 1609377-90-3 C₃₆H₄₁F₃N₂O₆ 
• 1609377-93-6 C₃₈H₄₅F₂N₃O₂ 
• 1609377-94-7 C₄₇H₅₀F₃N₃O₅ 
• 1609378-00-8 C₃₈H₄₅F₂N₃O₂ 
• 1609378-01-9 C₄₇H₅₀F₃N₃O₅ 
• 1609378-03-1 C₆₅H₈₁F₅N₆O₆ 

Relevant articles and documents

Folding-induced folding: The assembly of aromatic amide and 1,2,3-triazole hybrid helices

Folding-induced folding for the construction of artificial hybrid helices from two different kinds of aromatic sequences is described. Linear compounds 1a, 1b, and 2, containing one aromatic amide trimer or pentamer and one or two aromatic 1,2,3-triazole tetramers, have been designed and synthesized. The trimeric and pentameric amide segments are driven by intramolecluar N-HF hydrogen bonding to adopt a folded or helical conformation, whereas the triazole segment is intrinsically disordered. In organic solvents of low polarity, the amide foldamer segment induces the attached triazole segment(s) to fold through intramolecular stacking, leading to the formation of hybrid helices. The helical conformation of these hybrid sequences has been confirmed by 1H and 19F NMR spectroscopy, UV/Vis spectroscopy, circular dichroism (CD) experiments, and theoretical calculations. It was found that the amide pentamer exhibits a stronger ability to induce the folding of the attached triazole segment(s) compared with that of the shorter trimer. Enantiomers (R)-3 and (S)-3, which contain an R-or S-(1-naphthyl)ethylamino group at the end of a tetraamide segment, have also been synthesized. CD experiments showed that introduction of a chiral group caused the whole framework to produce a strong helicity bias. Densityfunctional-theory calculations on (S)-3 suggested that this compound exists as a right-handed (P) helix.