169531-06-0

Basic information

• Product Name: (S)-4-[(E)-3-(3-Amino-2-bromo-phenoxy)-propenyl]-2,2-dimethyl-oxazolidine-3-carboxylic acid tert-butyl ester
• CAS NO: 169531-06-0
• Molecular Weight: 427.338
• Mol File: 169531-06-0.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: (S)-4-[(E)-3-(3-Amino-2-bromo-phenoxy)-propenyl]-2,2-dimethyl-oxazolidine-3-carboxylic acid tert-butyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: (S)-4-[(E)-3-(3-Amino-2-bromo-phenoxy)-propenyl]-2,2-dimethyl-oxazolidine-3-carboxylic acid tert-butyl ester(169531-06-0)
• EPA Substance Registry System: (S)-4-[(E)-3-(3-Amino-2-bromo-phenoxy)-propenyl]-2,2-dimethyl-oxazolidine-3-carboxylic acid tert-butyl ester(169531-06-0)

Safety Data

• Hazardous Substances Data: 169531-06-0(Hazardous Substances Data)

Upstream product

• 168335-63-5 Hexanoic acid 2-bromo-3-(2,2-dimethyl-propionylamino)-phenyl ester 
• 168335-61-3 N-(2-bromo-3-methoxyphenyl)-2,2-dimethylpropionamide 
• 129483-65-4 (4S)-1,1-Dimethylethyl 4-<(E)-3'-methoxy-3'-oxo-1'-propenyl>-2,2-dimethyl-3-oxazolidinecarboxylate 
• 95715-87-0 (R)-3-tert-butoxycarbonyl-4-formyl-2,2-dimethyloxazolidine 
• 130532-54-6 (S)-((1E)-3-hydroxy-propenyl)-2,2-dimethyl-oxazolidine-3-carboxylic acid tert-butyl ester 
• 100367-36-0 2-bromo-3-hydroxyaniline 

Downstream Products

• 168335-67-9 (S)-4-[4-((S)-1-Benzyloxycarbonyl-2-methyl-propylamino)-benzofuran-3-ylmethyl]-2,2-dimethyl-oxazolidine-3-carboxylic acid tert-butyl ester 

Relevant articles and documents

Effect of alteration of the heterocyclic nucleus of ILV on its isoform selectivity for PKC. Palladium catalyzed route to benzofuran analogues of ILV

A palladium catalyzed route for the preparation of several benzofuran analogues of the PKC activator indolactam V (ILV) is described together with the ability of these compounds to activate the isoforms of PKC. The benzofuran analogues of ILV are shown to activate PKC with a slightly different pattern of isotype selectivity than ILV or 7-n-octyl-ILV. Moreover, in an examination of the effect of stereochemistry at the C-14 center of the teleocidins on PKC binding activity, a clear preference for R-stereochemistry at the C-14 center was found, thus providing additional verification of previously published structural correlations between the families of PKC activators.