17996-13-3

Basic information

• Product Name: 4-(Z-AMINO)-1-BUTANOL
• Synonyms: 4-(Z-AMINO)-1-BUTANOL;BENZYL N-(4-HYDROXYBUTYL)CARBAMATE;N-CARBOBENZOXY-DELTA-AMINO-N-BUTYL ALCOHOL;N-CARBOBENZOXY-4-AMINO-1-BUTANOL;Z-ABU(4)-OL;Z-NH-(CH2)4-OH;4-N-CBZ-AMINO-BUTAN-1-OL ;(4-Hydroxy-butyl)-carbamic acid benzyl ester
• CAS NO: 17996-13-3
• Molecular Formula: C₁₂H₁₇NO₃
• Molecular Weight: 223.27
• Mol File: 17996-13-3.mol
• Article Data: 32

Chemical Properties

• Melting Point: 81-84 °C
• Boiling Point: 397.1°Cat760mmHg
• Flash Point: 193.9°C
• Appearance: /
• Density: 1.127
• Vapor Pressure: 5.12E-07mmHg at 25°C
• Refractive Index: 1.53
• BRN: 2214428
• CAS DataBase Reference: 4-(Z-AMINO)-1-BUTANOL(CAS DataBase Reference)
• NIST Chemistry Reference: 4-(Z-AMINO)-1-BUTANOL(17996-13-3)
• EPA Substance Registry System: 4-(Z-AMINO)-1-BUTANOL(17996-13-3)

Safety Data

• Hazard Codes: Xn
• Statements: 22-36
• Safety Statements: 26
• WGK Germany: 3
• Hazardous Substances Data: 17996-13-3(Hazardous Substances Data)

Usage

General Description

4-(Z-AMINO)-1-BUTANOL, also known as 4-(Z-amino)-1-butanol, is a chemical compound with the molecular formula C4H11NO. 4-(Z-AMINO)-1-BUTANOL is a type of alcohol, with a butanol backbone and an amino group attached to the fourth carbon in the chain. It is commonly used as a building block in the synthesis of pharmaceuticals and agrochemicals, as well as in the production of surfactants and other specialty chemicals. 4-(Z-AMINO)-1-BUTANOL is also used as a chiral auxiliary in asymmetric synthesis reactions due to the presence of a chiral center in its structure. The Z-configuration of the amino group indicates that it is in the cis orientation with respect to the hydroxyl group on the third carbon atom. Overall, 4-(Z-AMINO)-1-BUTANOL has diverse applications in the field of organic chemistry and is an important intermediate in the synthesis of various compounds.

InChI:InChI=1/C12H17NO3/c14-9-5-4-8-13-12(15)16-10-11-6-2-1-3-7-11/h1-3,6-7,14H,4-5,8-10H2,(H,13,15)

Upstream product

• 13325-10-5 4-Aminobutanol 
• 501-53-1 benzyl chloroformate 
• 1346132-49-7 C₂₈H₃₅NO₃Si 
• 14468-80-5 N-benzyloxycarbonylpyrrolidin-2-one 
• 13139-17-8 N-(Benzyloxycarbonyloxy)succinimide 
• 67706-63-2 4-benzyloxycarbonylaminobutyric acid methyl ester 
• 137160-76-0 acetone O-(benzyloxycarbonyl)oxime 

Downstream Products

• 25070-74-0 1-benzyloxycarbonylpyrrolidine 
• 123348-75-4 N-phenylmethoxycarbonyl-N-propyl-1,4-diaminobutane 
• 114684-75-2 ΔLys(Cbz)*NCA 
• 114684-77-4 Boc-ΔLyz(Cbz)-OMe 
• 89965-56-0 <3-<<4-(carboxyamino)butyl>amino>propyl>carbamic acid, dibenzyl ester 
• 114684-73-0 Cbz-δLyz(Cbz)-OH 
• 123348-77-6 {4-[Acetyl-(3-benzyloxycarbonylamino-propyl)-amino]-butyl}-carbamic acid benzyl ester 
• 114684-71-8 Cbz-ΔLys(Cbz)-OMe 
• 123348-76-5 C₃₀H₃₁N₂O₂P 
• 123348-74-3 N-Phenylmethoxycarbonyl-N'-(2-methylpropyl)-1,4-diaminobutane 
• 1155373-98-0 4-(benzyloxycarbonylamino)butyl acetate 
• 1230072-98-6 benzyl (2S)-2-[2-oxopropyl]pyrrolidine-1-carboxylate 
• 1346132-33-9 benzyl-(2R)-2-(2’-oxopropyl) pyrrolidine-1-carboxylate 
• 118743-83-2 5-Acetoxy-3(S)-(4-benzyloxycarbonylaminobutyl)-N-<(R)-(-)-α-methylbenzyl>isoxazolidine 

Relevant articles and documents

DEUTERATED FORMS OF AMINOSTEROLS AND METHODS OF USING THE SAME

Described are deuterated forms of aminosterols, or a pharmaceutically acceptable salt thereof, wherein one or more hydrogen atoms at one or more positions selected from C1, C2, C3, C4, C5, C6, C7, C8, C9, C11, C12, C14, C15, C16, C17, C18, C19, C20, C21,

Synthesis method of double different protected amino acids

The invention relates to a synthesis method of double different protected amino acids.The technical problems of harsh reaction conditions, inapplicability of production enlarging and the like in an existing synthesis method are mainly solved. According to the technical scheme, the synthesis method of double different protected amino acids comprises the following steps: one of Boc20, Alloc-Cl or Cbz-Osuis added to amino alcohol under the action of an alkaline reagent to obtain a compound 1; the compound 1 reacts with methanesulfonyl chloride or paratoluensulfonyl chloride to obtain an intermediate, then a halide is added into acetone, heating and refluxing are executed to obtain a compound 2; the compound 2 is condensed with diethyl acetamidomalonate under the action of an alkaline agent togenerate a compound 3; the compound 3 is dissolved in alcohol and water, an inorganic base is added, heating, hydrolyzing and decarboxylating are executed to obtain a compound 4; acetylase is added into deionized water to obtain a compound 5 through enzymolysis; amino acid protection is executed, wherein one of Fmoc-Osu, Cbz-OSu, Alloc-Cl or Boc20 is added into thecompound 5 under the action of an alkaline agent to generatea target compound A.

CYCLIC KETO-AMIDE COMPOUNDS AS CALPAIN MODULATORS AND METHODS OF PRODUCTION AND USE THEREOF

The present technology relates to cyclic keto-amide compounds of general formulae I to XXXII, compositions and kits thereof as calpain modulators and methods useful for the treatment of various diseases or disorders such as fibrotic disease or cancer whic