189180-18-5Relevant articles and documents
Synthesis of derivatives of artesunate α-aminophosphonate and their antimicrobial activities
He, Sheng,Ouyang, Xilin,Huang, Xiaochao,Hu, Weisong,Dai, Weilong,Tian, Xiaoyan,Pan, Yingming,Huang, Shiwen,Wang, Hengshan
, p. 408 - 416 (2015/06/22)
Thirteen α-aminophosphonate derivatives with artesunate were synthesized by introducing bioactive α-aminophosphonate combination with artesunate in this work. The reaction were easily carried out at normal pressure, low temperature and without any catalys
Coumarin-containing aminophosphonates bridged with chiral side chain: Synthesis and influence of chirality on cytotoxicity and DNA binding
Li, Ya-Jun,Ye, Man-Yi,Huang, Ri-Zhen,Yao, Gui-Yang,Pan, Ying-Ming,Liao, Zhi-Xin,Wang, Heng-Shan
, p. 3144 - 3156 (2014/05/06)
A series of novel coumarin-containing α-Aminophosphonates with two chiral centers were synthesized and a single-crystal structure of compound 8g (8g', (R)-diethyl ((S)-2-(4-methyl-2-oxo-2H-chromen-7-yloxy)propanamido)(2- bromophenyl)methylphosphonate) was
Synthesis and antitumor activities of novel rhein α-aminophosphonates conjugates
Yao, Gui-Yang,Ye, Man-Yi,Huang, Ri-Zhen,Li, Ya-Jun,Pan, Ying-Ming,Xu, Qing,Liao, Zhi-Xin,Wang, Heng-Shan
supporting information, p. 501 - 507 (2014/01/23)
Several rhein α-aminophosphonates conjugates (5a-5q) were synthesized and evaluated for in vitro cytotoxicity against HepG-2, CNE, Spca-2, Hela and Hct-116 cell lines. Some compounds showed relatively high cytotoxicity. Especially, compound 5i exhibited t