215868-81-8

Basic information

• Product Name: (1-ETHYL-1H-1,2,4-TRIAZOL-5-YL)METHANOL
• Synonyms: (1-ETHYL-1H-1,2,4-TRIAZOL-5-YL)METHANOL
• CAS NO: 215868-81-8
• Molecular Formula: C₅H₉N₃O
• Molecular Weight: 127.15
• Mol File: 215868-81-8.mol
• Article Data: 5

Chemical Properties

• Boiling Point: 292.2±42.0 °C(Predicted)
• Appearance: /
• Density: 1.26±0.1 g/cm3(Predicted)
• Storage Temp.: 2-8°C
• PKA: 13.19±0.10(Predicted)
• CAS DataBase Reference: (1-ETHYL-1H-1,2,4-TRIAZOL-5-YL)METHANOL(CAS DataBase Reference)
• NIST Chemistry Reference: (1-ETHYL-1H-1,2,4-TRIAZOL-5-YL)METHANOL(215868-81-8)
• EPA Substance Registry System: (1-ETHYL-1H-1,2,4-TRIAZOL-5-YL)METHANOL(215868-81-8)

Safety Data

• Hazardous Substances Data: 215868-81-8(Hazardous Substances Data)

Usage

General Description

(1-Ethyl-1H-1,2,4-triazol-5-yl)methanol is a chemical compound with the molecular formula C6H10N2O. It is a derivative of triazole, a five-membered ring compound containing three nitrogen atoms and two carbon atoms. (1-ETHYL-1H-1,2,4-TRIAZOL-5-YL)METHANOL is commonly used in pharmaceutical and agricultural applications, specifically as a building block for the synthesis of pharmaceutical drugs and as a fungicide in agricultural products. It is also used in research and development as a reagent in organic synthesis. The compound may have potential medicinal and biological properties, although further research is needed to fully understand its effects and applications.

Upstream product

• 16778-70-4 1-ethyl-1H-1,2,4-triazole 
• 50-00-0 formaldehyd 
• 1034197-43-7 1-ethyl-1H-[1,2,4]triazole-3-carboxylic acid methyl ester 
• 1034197-44-8 methyl 1-ethyl-1H-1,2,4-triazole-5-carboxylate 
• 68-12-2 N,N-dimethyl-formamide 

Downstream Products

• 252977-51-8 TPA023 
• 367281-10-5 3-cyclopentyl-2-(2-ethyl-2H-[1,2,4]triazol-3-ylmethoxy)-7-(2-fluorophenyl)-4-methylpyrazolo[1,5-d][1,2,4]triazine 
• 367281-15-0 3-cyclopentyl-2-(2-ethyl-2H-[1,2,4]triazol-3-ylmethoxy)-4-methyl-7-phenyl-pyrazolo[1,5-d][1,2,4]triazine 
• 367281-18-3 3-tert-butyl-7-(2,5-difluorophenyl)-2-(2-ethyl-2H-[1,2,4]triazol-3-ylmethoxy)-4-methylpyrazolo[1,5-d][1,2,4]triazine 
• 1261174-53-1 7-(d9-tert-butyl)-6-((1-ethyl-1H-1,2,4-triazol-5-yl)methoxy)-3-(2-fluorophenyI)-[1,2,4]triazolo[4,3-b]pyridazine 
• 1261174-58-6 2-(6-((1-ethyl-1H-1,2,4-triazol-5-yl)methoxy)-3-(2-fluorophenyl)-[1,2,4]triazolo[4,3-b]pyridazin-7-yl)propan-1,1,1,3,3,3-d6-2-ol 
• 913532-50-0 C₁₂H₁₆N₄O 
• 265643-28-5 2-(2-ethyl-2H-[1,2,4]triazol-3-ylmethoxy)-3,7-bis(2-fluorophenyl)pyrazolo[1,5-d][1,2,4]triazine 

Relevant articles and documents

DEUTERIUM-MODIFIED TRIAZOLO-PYRIDAZINE DERIVATIVES AS GABA-A RECEPTOR MODULATORS

This invention relates to deuterated substituted triazolo-pyridazines and pharmaceutically acceptable salts thereof. This invention also provides compositions comprising a compound of this invention and the use of such compositions in methods of treating diseases and conditions that are beneficially treated by administering an αl-GABAA receptor antagonist or an α2- and/or an α3-GABAA receptor partial agonist.

7-(1,1-Dimethylethyl)-6-(2-ethyl-2H-1,2,4-triazol-3-ylmethoxy) -3-(2-fluorophenyl)-1,2,4-triazolo[4,3-b]pyridazine: A functionally selective γ-aminobutyric acidA (GABAA) α2/α3- subtype selective agonist that exhibits potent anxiolyti

There is increasing evidence that compounds with selectivity for γ-aminobutyric acidA (GABAA) α2- and/or α3-subtypes may retain the desirable anxiolytic activity of nonselective benzodiazepines but possess an improved side effect pro

Substituted 1,2,4-triazolo[3,4-a]phthalazine derivatives as GABA alpha 5 ligands

Substituted 1,2,4-Triazolo[3,4-A]phthalazine derivatives are GABA Alpha 5 ligands and are represented by the formula