29654-55-5Relevant articles and documents
Resorcinarenes as templates: A general strategy for the synthesis of large macrocycles
Li, Xuehe,Upton, Thomas G.,Gibb, Corinne L. D.,Gibb, Bruce C.
, p. 650 - 651 (2003)
The concept that resorcinarenes can be used as templates for the synthesis of large macrocycles is introduced. By way of example, previously inaccessible, aromatic crown ethers compounds are synthesized. Copyright
Synthesis of 3, 5 - dihydroxy benzaldehyde method (by machine translation)
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Paragraph 0030-0037, (2019/10/04)
The invention discloses a method for synthesizing 3, 5 - dihydroxy benzaldehyde of the method, the synthetic route is: first 3, 5 - dihydroxy benzoic acid sodium borohydride, dimethyl sulfate, boric acid under the action of the three methyl ester intermediate B obtained, then intermediate B in chromium trioxide and sulfuric acid to obtain compound under the action of the C, i.e. 3, 5 - dihydroxy benzaldehyde; reaction is: The invention of mild synthetic conditions, the reaction yield is high, and the process of the method is simple, the raw material is cheap, simple and convenient operation, is extremely suitable for industrial production, has a very wide range of industrial application and market value. (by machine translation)
Preparation method of 3,5-dihydroxybenzyl alcohol
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Paragraph 0007; 0011; 0013, (2017/05/27)
The invention relates to a preparation method of a medical and chemical intermediate 3,5-dihydroxybenzyl alcohol. The method comprises the following steps of: with commercially available 3,5-dihydroxy-benzoic acid as a raw material, preparing 3,5-diacetoxybenzoic acid through an acetylation reaction; reducing carboxyl into alcohol by a sodium borohydride/iodine borohydride system; and finally, performing acetyl de-protection using a weak base solution to obtain the target product 3,5-dihydroxybenzyl alcohol. The synthesis path has the characteristics of cheap and easily available reagent, mild reaction conditions, easiness in operation, easiness in product separation, relatively high yield and the like.