30058-40-3 Usage
Description
2-Fluorobenzenesulfonamide is an organic compound that can be synthesized by reacting 2-fluorobenzenesulfonyl chloride with 50% ammonium hydroxide in tetrahydrofuran. It is a white solid with various potential applications in different industries due to its unique chemical properties.
Uses
Used in Pharmaceutical Industry:
2-Fluorobenzenesulfonamide is used as an intermediate for the synthesis of various pharmaceutical compounds. Its unique chemical structure allows it to be a versatile building block in the development of new drugs, particularly those targeting specific biological pathways.
Used in Chemical Synthesis:
2-Fluorobenzenesulfonamide is used as a reagent in the chemical synthesis of various organic compounds. Its fluorinated nature and benzene ring make it a valuable component in the creation of complex molecules for research and industrial applications.
Used in Research and Development:
2-Fluorobenzenesulfonamide is used as a research compound for studying the effects of fluorination on the properties and reactivity of benzene-based molecules. This can lead to a better understanding of the role of fluorine in chemical reactions and the development of new synthetic methods.
Used in Material Science:
2-Fluorobenzenesulfonamide can be used in the development of new materials with specific properties, such as improved thermal stability or chemical resistance. Its unique structure and properties make it a potential candidate for use in the creation of advanced materials for various applications.
Used in Analytical Chemistry:
2-Fluorobenzenesulfonamide can be used as a reference compound or standard in analytical chemistry for the calibration of instruments and the development of new analytical methods. Its distinct chemical properties make it a valuable tool for researchers in this field.
Check Digit Verification of cas no
The CAS Registry Mumber 30058-40-3 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 3,0,0,5 and 8 respectively; the second part has 2 digits, 4 and 0 respectively.
Calculate Digit Verification of CAS Registry Number 30058-40:
(7*3)+(6*0)+(5*0)+(4*5)+(3*8)+(2*4)+(1*0)=73
73 % 10 = 3
So 30058-40-3 is a valid CAS Registry Number.
InChI:InChI=1/C6H6FNO2S/c7-5-3-1-2-4-6(5)11(8,9)10/h1-4H,(H2,8,9,10)
30058-40-3Relevant articles and documents
NOVEL OXADIAZOLES
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Page/Page column 91, (2019/08/26)
The present invention relates to novel oxadiazoles of Formula I, wherein, R1, L1, A, L2 and R10 are as defined in the detailed description.
Design and synthesis of triazolopyrimidine acylsulfonamides as novel anti-mycobacterial leads acting through inhibition of acetohydroxyacid synthase
Patil, Vikas,Kale, Manoj,Raichurkar, Anandkumar,Bhaskar, Brahatheeswaran,Prahlad, Dwarakanath,Balganesh, Meenakshi,Nandan, Santosh,Shahul Hameed
supporting information, p. 2222 - 2225 (2014/05/06)
Novel triazolopyrimidine acylsulfonamides class of antimycobacterial agents, which are mycobacterial acetohydroxyacid synthase (AHAS) inhibitors were designed by hybridization of known AHAS inhibitors such as sulfonyl urea and triazolopyrimidine sulfonamides. This Letter describes the synthesis and SAR studies of this class of molecules by variation of two parts of the molecule, the phenyl and triazolopyrimidine rings. SAR study describes optimisation of enzyme potency, whole cell potency and evidence of mechanism of action.
Convenient Approach to 3,4-Diarylisoxazoles Based on the Suzuki Cross-Coupling Reaction
Dileep Kumar,Ho, ManKit M.,Leung, Jennifer M.,Toyokuni, Tatsushi
, p. 1146 - 1151 (2007/10/03)
The Suzuki cross-coupling reaction was found effective for rapid access to a series of 3,4-diarylisoxazoles of pharmacological interest. The efficiency of this approach was demonstrated by the synthesis of the highly potent COX-2-selective inhibitor, 4-(5-methyl-3-phenyl-4-isoxazolyl)benzenesulfonamide (valdecoxib), and its analogues. Thus, the coupling reaction between (3-aryl-5-methyl-4-isoxazolyl)boronic acids, prepared in situ from the corresponding bromides using triisopropyl borate, and aryl bromides containing a 4-sulfonamide or 4-methylsulfonyl group under the standard conditions [Pd(PPh3)4, Na2CO3, EtOH-H2O, reflux] yielded the target 3,4-diarylisoxazoles in good yields.