32742-35-1

Basic information

• Product Name: 1,4-anhydro-D-galactitol
• Synonyms: 1,4-anhydro-D-galactitol
• CAS NO: 32742-35-1
• Molecular Weight: 164.158
• Mol File: 32742-35-1.mol
• Article Data: 64

Chemical Properties

• CAS DataBase Reference: 1,4-anhydro-D-galactitol(CAS DataBase Reference)
• NIST Chemistry Reference: 1,4-anhydro-D-galactitol(32742-35-1)
• EPA Substance Registry System: 1,4-anhydro-D-galactitol(32742-35-1)

Safety Data

• Hazardous Substances Data: 32742-35-1(Hazardous Substances Data)

Upstream product

• 535-94-4 β-D-Glcp-(1->4)-D-glucitol 
• 50-70-4 D-sorbitol 
• 488-43-7 1-Amino-1-deoxy-D-glucitol 
• 69-65-8 mannitol 
• 3615-41-6 L-Rhamnose 
• 9004-34-6 cellulose 
• 59-23-4 D-Galactose 
• 50-99-7 D-glucose 
• 608-66-2 D-galactitol 
• 3458-28-4 D-Mannose 
• 5996-10-1 glucose monohydrate 
• 1769-00-2 1,2,3,4,6-penta-O-trimethylsilyl-α-D-glucopyranose 
• 3615-56-3 D-Sorbose 
• 7697-37-2 nitric acid 

Downstream Products

• 652-67-5 Isosorbide 
• 39798-51-1 tri-O-benzoyl-6-iodo-1,4-anhydro-6-deoxy-D-glucitol 
• 39798-50-0 O²,O³,O⁵-tribenzoyl-O⁶-(toluene-4-sulfonyl)-1,4-anhydro-D-glucitol 
• 5938-38-5 sorbitan monooleate 
• 1424709-54-5 1,4-anhydro-6-O-trityl-D-sorbitol 
• 1424709-76-1 6-O-allyl-1,4-anhydro-2,3,5-tri-O-benzyl-D-sorbitol 
• 1424709-70-5 1,4-anhydro-2,3,5-tri-O-benzyl-D-sorbitol 
• 1424709-66-9 1,4-anhydro-5,6-O-isopropylidene-2-O-p-methoxybenzoyl-D-sorbitol 
• 1424709-64-7 1,4-anhydro-2-O-p-methoxybenzoyl-D-sorbitol 
• 101069-30-1 methyl <2S-<2α(4R),3β(Z),4α>>-7-<4-(tert-butyldiphenylsilyloxy)-2-(2,2-dimethyl-1,3-dioxolan-4-yl)-tetrahydrofuran-3-yl>-5-heptenoate 
• 101069-35-6 (Z)-7-[(2S,3R,4S)-4-(tert-Butyl-diphenyl-silanyloxy)-2-(2,2-dimethyl-[1,3]dioxolan-4-yl)-tetrahydro-furan-3-yl]-hept-5-enoic acid 
• 101069-28-7 1,4-anhydro-2-O-tert-butyldiphenylsilyl-3-deoxy-3-C-(ethoxycarbonylmethyl)-5,6-O-isopropylidene-D-allitol 
• 101069-28-7 1,4-anhydro-2-O-tert-butyldiphenylsilyl-3-deoxy-3-C-(ethoxycarbonylmethyl)-5,6-O-isopropylidene-D-altritol 
• 101069-29-8 1,4-anhydro-2-O-tert-butyldiphenylsilyl-3-deoxy-3-C-(formylmethyl)l-5,6-O-isopropylidene-D-allitol 

Relevant articles and documents

Sulfuric acid-catalyzed dehydration of sorbitol: Mechanistic study on preferential formation of 1,4-sorbitan

1,4-Sorbitan is a precursor to environmentally benign surfactants, which can be produced from biomass via sorbitol. Currently, sulfuric acid-catalyzed dehydration of sorbitol is the most widely used route for industrial synthesis of 1,4-sorbitan. In this work, we have studied the mechanism of the sorbitol dehydration by sulfuric acid. Our results show that both thermodynamic and kinetic parameters play significant roles to determine the yield of 1,4-sorbitan. Sorbitol preferentially forms an adduct with sulfuric acid, thereby inhibiting the subsequent dehydration of 1,4-sorbitan to isosorbide. Furthermore, a reaction mechanism is proposed for the dehydration reaction, which involves an SN2 reaction on primary C1 of sorbitol attacked by OH of secondary C4.

METHOD FOR PREPARATION OF 1,4-SORBITAN IN AQUEOUS MEDIUM

The invention discloses a method for preparation of 1,4-sorbitan by dehydration of D-sorbitol in aqueous medium, wherein one equivalent of water is removed and a cyclization occurs, followed by a treatment with ethanol and isopropanol.

Direct conversion of cellulose into isosorbide over Ni doped NbOPO4catalysts in water

Isosorbide is a versatile chemical intermediate for the production of a variety of drugs, chemicals, and polymers, and its efficient production from natural cellulose is of great significance. In this study, bifunctional catalysts based on niobium phosphates were prepared by a facile hydrothermal method and used for the direct conversion of cellulose to isosorbide under aqueous conditions. NH3-TPD analysis showed that a high acid content existed on the catalyst surface, and pyridine infrared spectroscopic analysis confirmed the presence of both Lewis acid and Br?nsted acid sites, both of which played an important role in the process of carbohydrate conversion. XRD and H2-TPR characterization determined the composition and the hydrogenation centers of the catalyst. An isosorbide yield of 47% could be obtained at 200 °C for 24 h under 3 MPa H2 pressure. The Ni/NbOPO4 bifunctional catalyst retains most of its activity after five consecutive runs with slightly decreased isosorbide yield of 44%. In addition, a possible reaction mechanism was proposed that the synergistic effect of surface acid sites and hydrogenation sites was favorable to enhancing the cascade dehydration and hydrogenation reactions during the conversion of cellulose to isosorbide. This study provides as an efficient strategy for the development of novel multifunctional heterogeneous catalysts for the one-pot valorisation of cellulose. This journal is