4248-21-9 Usage
Description
ETHYLHEXYLCARBAMATE, also known as EHC, is a chemical compound that serves as a preservative in various personal care products such as skin care, hair care, and sunscreen. It acts as a broad-spectrum antimicrobial agent, preventing the growth of bacteria, yeast, and mold in these products. EHC is favored for its effectiveness at low concentrations and its low potential for causing skin irritation or sensitization. However, there are concerns regarding potential health risks associated with long-term exposure to EHC, leading to some regulatory restrictions on its use in certain products.
Used in Personal Care Industry:
ETHYLHEXYLCARBAMATE is used as a preservative for personal care products to ensure their safety and stability. It is effective at low concentrations and has a low potential for causing skin irritation or sensitization, making it a preferred choice for preserving the quality and preventing microbial contamination of products like skin care, hair care, and sunscreen.
Used in Skin Care Products:
ETHYLHEXYLCARBAMATE is used as a preservative in skin care products to maintain their freshness and prevent the growth of harmful microorganisms. Its broad-spectrum antimicrobial properties help to protect the skin from potential infections and ensure the product's efficacy and safety.
Used in Hair Care Products:
ETHYLHEXYLCARBAMATE is used as a preservative in hair care products to maintain their quality and prevent microbial contamination. Its effectiveness at low concentrations and low potential for causing irritation make it suitable for preserving hair care products, ensuring their safety and stability.
Used in Sunscreen Products:
ETHYLHEXYLCARBAMATE is used as a preservative in sunscreen products to maintain their stability and prevent the growth of bacteria, yeast, and mold. Its broad-spectrum antimicrobial properties help to ensure the safety and effectiveness of sunscreen products, protecting the skin from harmful UV rays and potential infections.
Check Digit Verification of cas no
The CAS Registry Mumber 4248-21-9 includes 7 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 4 digits, 4,2,4 and 8 respectively; the second part has 2 digits, 2 and 1 respectively.
Calculate Digit Verification of CAS Registry Number 4248-21:
(6*4)+(5*2)+(4*4)+(3*8)+(2*2)+(1*1)=79
79 % 10 = 9
So 4248-21-9 is a valid CAS Registry Number.
InChI:InChI=1/C9H19NO2/c1-3-5-6-8(4-2)7-12-9(10)11/h8H,3-7H2,1-2H3,(H2,10,11)
4248-21-9Relevant articles and documents
Syntheses and evaluation of anticonvulsant activity of novel branched alkyl carbamates
Hen, Naama,Bialer, Meir,Yagen, Boris
experimental part, p. 2835 - 2845 (2012/06/15)
A novel class of 19 carbamates was synthesized, and their anticonvulsant activity was comparatively evaluated in the rat maximal electroshock (MES) and subcutaneous metrazol (scMet) seizure tests and pilocarpine-induced status epilepticus (SE) model. In spite of the alkyl-carbamates' close structural features, only compounds 34, 38, and 40 were active at the MES test. The analogues 2-ethyl-3-methyl-butyl-carbamate (34) and 2-ethyl-3-methyl-pentyl- carbamate (38) also exhibited potent activity in the pilocarpine-SE model 30 min postseizure onset. Extending the aliphatic side chains of homologous carbamates from 7 to 8 (34 to 35) and from 8 to 9 carbons in the homologues 38 and 43 decreased the activity in the pilocarpine-SE model from ED50 = 81 mg/kg (34) to 94 mg/kg (35) and from 96 mg/kg (38) to 114 mg/kg (43), respectively. The most potent carbamate, phenyl-ethyl-carbamate (47) (MES ED50 = 16 mg/kg) contains an aromatic moiety in its structure. Compounds 34, 38, 40, and 47 offer the optimal efficacy-safety profile and, consequently, are promising candidates for development as new antiepileptics.
Research in dipropylacetic series. XII. Aliphatic ramified acids and alcohols with anticonvulsant activity
Taillandier,Benoit Guyod,Boucherle,et al.
, p. 453 - 462 (2007/10/05)
Previous results obtained about 2 propyl pentanoic acid (dipropylacetic or DPA) have been extended to other dialkylalkanoic acids having less than 14 carbon atoms and to some of their precursors (alcohols) or derivatives (amides). The effect of lengthening the chain bonding between the carbon bearing the two alkyl chains and the functional carbon on about 50 molecules is discussed. The anticonvulsant activity's length and strength often increases when lengthening that chain.
