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493035-82-8

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493035-82-8 Usage

Description

(4-Hydroxy-2-methyl)phenylboronic acid is an organic compound with the molecular formula C7H9BO3. It features a boron atom bonded to a phenyl ring, with a hydroxyl group at the 4th position and a methyl group at the 2nd position. (4-Hydroxy-2-methyl)phenylboronic acid is known for its reactivity and is commonly used in organic synthesis and pharmaceutical applications.

Uses

Used in Chemical Synthesis:
(4-Hydroxy-2-methyl)phenylboronic acid is used as a key reactant in the Suzuki reaction, a widely employed method for the formation of carbon-carbon bonds, particularly in the synthesis of biaryl compounds. The reaction involves the cross-coupling of an aryl or vinyl halide with an organoboron compound, such as (4-Hydroxy-2-methyl)phenylboronic acid, in the presence of a palladium catalyst and a base.
Used in Pharmaceutical Industry:
(4-Hydroxy-2-methyl)phenylboronic acid is used as a reactant in the preparation of biarylmethoxy nicotinamides, which are specific inhibitors of Mycobacterium tuberculosis. These compounds have potential applications in the development of new antituberculosis drugs, targeting the bacteria responsible for tuberculosis and offering a promising alternative to existing treatments.

Check Digit Verification of cas no

The CAS Registry Mumber 493035-82-8 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 4,9,3,0,3 and 5 respectively; the second part has 2 digits, 8 and 2 respectively.
Calculate Digit Verification of CAS Registry Number 493035-82:
(8*4)+(7*9)+(6*3)+(5*0)+(4*3)+(3*5)+(2*8)+(1*2)=158
158 % 10 = 8
So 493035-82-8 is a valid CAS Registry Number.
InChI:InChI=1/C7H9BO3/c1-5-4-6(9)2-3-7(5)8(10)11/h2-4,9-11H,1H3

493035-82-8 Well-known Company Product Price

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  • TCI America

  • (H1495)  4-Hydroxy-2-methylphenylboronic Acid (contains varying amounts of Anhydride)  

  • 493035-82-8

  • 1g

  • 780.00CNY

  • Detail
  • TCI America

  • (H1495)  4-Hydroxy-2-methylphenylboronic Acid (contains varying amounts of Anhydride)  

  • 493035-82-8

  • 5g

  • 2,690.00CNY

  • Detail
  • Alfa Aesar

  • (H53068)  4-Hydroxy-2-methylbenzeneboronic acid, 98%   

  • 493035-82-8

  • 250mg

  • 811.0CNY

  • Detail
  • Alfa Aesar

  • (H53068)  4-Hydroxy-2-methylbenzeneboronic acid, 98%   

  • 493035-82-8

  • 1g

  • 2593.0CNY

  • Detail

493035-82-8SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 11, 2017

Revision Date: Aug 11, 2017

1.Identification

1.1 GHS Product identifier

Product name 4-Hydroxy-2-methylphenylboronic acid

1.2 Other means of identification

Product number -
Other names (4-Hydroxy-2-methylphenyl)boronic acid

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:493035-82-8 SDS

493035-82-8Relevant articles and documents

FARNESOID X RECEPTOR AGONISTS

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Page/Page column 82, (2008/06/13)

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