532-40-1 Usage
Description
THIAMINE MONOPHOSPHATE CHLORIDE, also known as Vitamin B1 Monophosphate Chloride, is a thiamine derivative produced by the enzyme thiamine pyrophosphatase. It is a crystalline substance that serves as a precursor to thiamine pyrophosphate (T344070), which is a cofactor essential for catalyzing various biochemical reactions in the body.
Uses
Used in Pharmaceutical Industry:
THIAMINE MONOPHOSPHATE CHLORIDE is used as a precursor for the production of thiamine pyrophosphate (T344070) for its role as a cofactor in catalyzing various biochemical reactions. This makes it an important component in the development of medications targeting conditions related to thiamine deficiency or those requiring enhanced thiamine activity.
Used in Nutritional Supplements:
THIAMINE MONOPHOSPHATE CHLORIDE is used as an active ingredient in nutritional supplements to support the body's energy production and maintain proper functioning of the nervous system. Its role in catalyzing biochemical reactions contributes to overall health and well-being.
Used in Research and Development:
In the field of research and development, THIAMINE MONOPHOSPHATE CHLORIDE is used as a key compound for studying the mechanisms of thiamine pyrophosphate and its effects on various biological processes. This helps in understanding the potential therapeutic applications of thiamine and its derivatives in treating specific health conditions.
Used in Food Industry:
THIAMINE MONOPHOSPHATE CHLORIDE can be used as an additive in the food industry to enhance the nutritional value of certain products, particularly those aimed at addressing thiamine deficiency or promoting overall health. Its role in energy production and nervous system function makes it a valuable component in the development of fortified foods and beverages.
Flammability and Explosibility
Notclassified
Purification Methods
Purify it by recrystallisation from aqueous HCl, EtOH slightly acidified with HCl, EtOH/Me2CO, H2O, or H2O/EtOH/Et2O. Dissolve it in a small volume of H2O and mix it with EtOH/Me2CO (1:1) to give the HCl.H2O as crystals. Filter it off, wash it with Et2O and dry it in a vacuum. The chloride hydrochloride, m 215-217o(dec) is obtained when it is crystallised from aqueous HCl. [Wenz et al. Justus Liebigs Ann Chem 618 2280 1958, Viscontini et al. Helv Chim Acta 34 1388 1951, Leichssenring & Schmidt Chem Ber 95 767 1962, McCormick & Wright Methods Enzymol 18A 141, 147 1970, Beilstein 27 III/IV 1766.]
Check Digit Verification of cas no
The CAS Registry Mumber 532-40-1 includes 6 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 3 digits, 5,3 and 2 respectively; the second part has 2 digits, 4 and 0 respectively.
Calculate Digit Verification of CAS Registry Number 532-40:
(5*5)+(4*3)+(3*2)+(2*4)+(1*0)=51
51 % 10 = 1
So 532-40-1 is a valid CAS Registry Number.
InChI:InChI=1/C12H17N4O4PS.ClH/c1-8-11(3-4-20-21(17,18)19)22-7-16(8)6-10-5-14-9(2)15-12(10)13;/h5,7H,3-4,6H2,1-2H3,(H3-,13,14,15,17,18,19);1H
532-40-1Relevant articles and documents
Benfotiamine related substance, preparation method, application and detection method
-
Paragraph 0028-0030, (2021/05/12)
The invention discloses a benfotiamine related substance, a preparation method, application and a detection method. The benfotiamine related substance is a compound C, and the structure of the compound C is shown in the description. The preparation method provided by the invention is simple, and the compound C with the purity meeting the requirement can be prepared. The invention further provides the detection method of the benfotiamine related substance. The high-purity compound C can be used as a benfotiamine reference substance or standard substance, and has a good application prospect.
A PROCESS FOR THE PREPARATION OF A THIAMINE DERIVATIVE AND SALT THEREOF
-
Page/Page column 7; 8, (2016/06/20)
A process for the preparation of a thiamine derivative and salt thereof, the process comprising the steps of: reacting thiamine chloride hydrochloride with phosphoric acid in the presence of a catalyst to produce a reaction mass of thiamine polyphosphates; isolating said thiamine derivative from said reaction mass of thiamine polyphosphates; and preparing salt of said thiamine derivative.