5455-59-4 Usage
Description
2-Nitrobenzenesulfonamide is a carbonic anhydrase inhibitor, characterized by its yellow to light brown crystalline powder appearance. It is a chemical compound with significant applications in various industries due to its unique properties.
Uses
Used in Pharmaceutical Industry:
2-Nitrobenzenesulfonamide is used as a pharmaceutical agent for its carbonic anhydrase inhibitory properties. It plays a crucial role in the treatment of conditions that involve the regulation of acid-base balance in the body, such as glaucoma, certain types of epilepsy, and altitude sickness. By inhibiting carbonic anhydrase, it helps in reducing intraocular pressure and preventing the overproduction of carbon dioxide, which can lead to these medical conditions.
Used in Chemical Research:
In the field of chemical research, 2-Nitrobenzenesulfonamide serves as an important compound for studying the mechanisms of carbonic anhydrase enzymes and their role in various biological processes. Its use in research contributes to the development of new drugs and therapies targeting carbonic anhydrase-related diseases.
Used in Environmental Applications:
2-Nitrobenzenesulfonamide can also be utilized in environmental applications, such as water treatment and pollution control. Its ability to inhibit carbonic anhydrase can be leveraged to control the growth of certain microorganisms and algae that contribute to water pollution. This application helps in maintaining the ecological balance and ensuring the availability of clean water resources.
Check Digit Verification of cas no
The CAS Registry Mumber 5455-59-4 includes 7 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 4 digits, 5,4,5 and 5 respectively; the second part has 2 digits, 5 and 9 respectively.
Calculate Digit Verification of CAS Registry Number 5455-59:
(6*5)+(5*4)+(4*5)+(3*5)+(2*5)+(1*9)=104
104 % 10 = 4
So 5455-59-4 is a valid CAS Registry Number.
InChI:InChI=1/C6H6N2O4S/c7-13(11,12)6-4-2-1-3-5(6)8(9)10/h1-4H,(H2,7,11,12)
5455-59-4Relevant articles and documents
Conformational properties of ortho-nitrobenzenesulfonamide in gas and crystalline phases. Intra- and intermolecular hydrogen bond
Giricheva, Nina I.,Girichev, Georgiy V.,Medvedeva, Yulia S.,Ivanov, Sergey N.,Bardina, Anna V.,Petrov, Vyacheslav M.
, p. 373 - 383 (2011)
A combined gas-phase electron diffraction and quantum chemical (B3LYP/6-311+G, B3LYP/cc-pvtz, MP2/cc-pvtz) study of molecular structure of 2-nitrobenzenesulfonamide (2-NBSA) was carried out. Quantum chemical calculations showed that 2-NBSA has four confor
MYELINATION STIMULATOR COMPOUNDS, AND METHODS OF TREATMENT
-
, (2019/11/28)
The invention is directed towards compounds, methods of stimulating myelination, stimulating proliferation of oligodendrocytes (OLs) or stimulating oligodendrocyte precursor cells and methods of treating diseases, disorders or symptoms thereof.
Synthesis of (-)-Cytisine Using a 6- endo aza-Michael Addition
Barát, Viktor,Csókás, Dániel,Bates, Roderick W.
supporting information, p. 9088 - 9095 (2018/07/25)
An asymmetric synthesis of (-)-cytisine has been achieved. The piperidine C-ring was formed using a stereodivergent intramolecular 6-endo aza-Michael addition. The B-ring was established by intramolecular pyridine N-alkylation. The absolute stereochemistry was established by an Evans acyl oxazolidinone enolate alkylation reaction that proceeded with an unexpected stereochemical outcome due to participation of the pyridine nitrogen lone pair.
