6011-18-3Relevant articles and documents
Copper-Catalyzed Three-Component Domino Cyclization for the Synthesis of 4-Aryl-5-(arythio)-2-(trifluoromethyl)oxazoles
Xiao, Fuhong,Yuan, Shanshan,Huang, Huawen,Zhang, Feng,Deng, Guo-Jun
supporting information, p. 8533 - 8536 (2019/10/17)
A copper-catalyzed oxidative cyclization of oxime, arylthiol, and trifluoroacetic anhydride for the construction of trisubstituted oxazoles has been developed. This transformation combines N-O bond cleavage, C-H functionalization, and intramolecular annulation, providing a practical protocol for the introduction of a trifluoromethyl (-CF3) group at oxazole rings.
Synthesis of ketoximes via a solvent-assisted and robust mechanochemical pathway
Aakeroey, Christer B.,Sinha, Abhijeet S.
, p. 8168 - 8171 (2013/09/02)
A versatile and robust mechanochemical route to ketone-oxime conversions has been established for a broad range of ketones via a simple mortar-pestle grinding method. The relative reactivity of aldehydes vs. ketones under these conditions has also been explored, along with an examination of the possible connection between reactivity and electronic substituent effects.
Highly effective receptors showing di- vs. monosaccharide preference
Mazik, Monika,Buthe, Arno C.
scheme or table, p. 1558 - 1568 (2008/10/09)
Receptors 1 and 2, incorporating two heterocyclic recognition units as well as oxime- or hydroxymethyl-based hydrogen-bonding sites, were prepared, and their binding properties toward neutral sugars were determined. The design of these receptors was inspi