644-36-0 Usage
Description
2-Methylphenylacetic acid, also known as o-Tolylacetic acid, is a ring-substituted phenylacetic acid that exhibits auxin activity. It is a naturally occurring plant hormone that plays a crucial role in the regulation of plant growth and development.
Used in Agriculture:
2-Methylphenylacetic acid is used as a plant growth regulator for promoting growth and development in various crops. It helps in increasing the yield and quality of agricultural products by stimulating cell elongation, division, and differentiation.
Used in Pharmaceutical Industry:
2-Methylphenylacetic acid is used as an intermediate in the synthesis of various pharmaceutical compounds. Its auxin activity makes it a valuable component in the development of drugs targeting plant growth-related disorders and conditions.
Used in Cosmetic Industry:
2-Methylphenylacetic acid is used as an active ingredient in some cosmetic products, particularly in anti-aging and skin care formulations. Its ability to regulate cell growth and differentiation can contribute to the improvement of skin health and appearance.
Used in Research:
2-Methylphenylacetic acid is utilized in scientific research to study the mechanisms of plant growth and development. It serves as a valuable tool for understanding the role of auxins in various biological processes and for developing new strategies for crop improvement and plant breeding.
Check Digit Verification of cas no
The CAS Registry Mumber 644-36-0 includes 6 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 3 digits, 6,4 and 4 respectively; the second part has 2 digits, 3 and 6 respectively.
Calculate Digit Verification of CAS Registry Number 644-36:
(5*6)+(4*4)+(3*4)+(2*3)+(1*6)=70
70 % 10 = 0
So 644-36-0 is a valid CAS Registry Number.
InChI:InChI=1/C9H10O2/c1-7-4-2-3-5-8(7)6-9(10)11/h2-5H,6H2,1H3,(H,10,11)/p-1
644-36-0Relevant articles and documents
HOMOGENEOUS AND PHASE TRANSFER CATALYZED CARBONYLATION REACTIONS
Alper, Howard
, p. 1 - 6 (1986)
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Visible-Light-Enabled Carboxylation of Benzyl Alcohol Derivatives with CO2 Using a Palladium/Iridium Dual Catalyst
Iwasawa, Nobuharu,Jin, Yushu,Toriumi, Naoyuki
, (2021/12/14)
A highly efficient carboxylation of benzyl alcohol derivatives with CO2 using a palladium/iridium dual catalyst under visible-light irradiation was developed. A wide range of benzyl alcohol derivatives could be employed to provide benzylic carboxylic acids in moderate to high yields. Mechanistic studies indicated that the oxidative addition of benzyl alcohol derivatives was possibly the rate-determining-step. It was also found that a switchable site-selective carboxylation between benzylic C?O and aryl C?Cl moieties could be achieved simply by changing the palladium catalyst.
Pd(OH)2/C, a Practical and Efficient Catalyst for the Carboxylation of Benzylic Bromides with Carbon Monoxide
Wakuluk-Machado, Anne-Marie,Dewez, Damien F.,Baguia, Hajar,Imbratta, Miguel,Echeverria, Pierre-Georges,Evano, Gwilherm
, p. 713 - 723 (2020/02/04)
A simple, efficient, cheap, and broadly applicable system for the carboxylation of benzylic bromides with carbon monoxide and water is reported. Upon simple reaction with only 2.5 wt % of Pearlman's catalyst and 10 mol % of tetrabutylammonium bromide in tetrahydrofuran at 110 °C for 4 h, a range of benzylic bromides can be smoothly converted to the corresponding arylacetic acids in good to excellent yields after simple extraction and acid-base wash. The reaction was found to be broadly applicable, scalable, and could be successfully extended to the use of ex situ-generated carbon monoxide and applied to the synthesis of the nonsteroidal anti-inflammatory drug diclofenac.