7579-40-0

Basic information

• Product Name: benzyl 2-chlorobenzoate
• Synonyms: benzyl 2-chlorobenzoate
• CAS NO: 7579-40-0
• Molecular Formula: C₁₄H₁₁ClO₂
• Molecular Weight: 246.68894
• Mol File: 7579-40-0.mol
• Article Data: 12

Chemical Properties

• Boiling Point: 356.2°Cat760mmHg
• Flash Point: 181.7°C
• Appearance: /
• Density: 1.233g/cm³
• Vapor Pressure: 2.96E-05mmHg at 25°C
• Refractive Index: 1.589
• CAS DataBase Reference: benzyl 2-chlorobenzoate(CAS DataBase Reference)
• NIST Chemistry Reference: benzyl 2-chlorobenzoate(7579-40-0)
• EPA Substance Registry System: benzyl 2-chlorobenzoate(7579-40-0)

Safety Data

• Hazardous Substances Data: 7579-40-0(Hazardous Substances Data)

Usage

InChI:InChI=1/C14H11ClO2/c15-13-9-5-4-8-12(13)14(16)17-10-11-6-2-1-3-7-11/h1-9H,10H2

Upstream product

• 103-83-3 N,N'-dimethylbenzylamine 
• 610-96-8 methyl chlorobenzoate 
• 609-65-4 o-chlorobenzoyl chloride 
• 100-51-6 benzyl alcohol 
• 89-98-5 2-chloro-benzaldehyde 
• 58824-52-5 α-vinyl-o-chlorobenzyl alcohol 
• 108-88-3 toluene 
• 100-39-0 benzyl bromide 
• 118-91-2 ortho-chlorobenzoic acid 
• 103-82-2 phenylacetic acid 
• 100-44-7 benzyl chloride 

Downstream Products

• 620-47-3 1-methyl-3-(phenylmethyl)-benzene 
• 620-83-7 1-methyl-4-(phenylmethyl)benzene 
• 713-36-0 2-benzyltoluene 
• 118-91-2 ortho-chlorobenzoic acid 

Relevant articles and documents

Photochemical Activation of Aromatic Aldehydes: Synthesis of Amides, Hydroxamic Acids and Esters

A cheap, facile and metal-free photochemical protocol for the activation of aromatic aldehydes has been developed. Utilizing thioxanthen-9-one as the photocatalyst and cheap household lamps as the light source, a variety of aromatic aldehydes have been activated and subsequently converted in a one-pot reaction into amides, hydroxamic acids and esters in good to high yields. The applicability of this method was highlighted in the synthesis of Moclobemide, a drug against depression and social anxiety. Extended and detailed mechanistic studies have been conducted, in order to determine a plausible mechanism for the reaction.

Reusable ionic liquid-catalyzed oxidative esterification of carboxylic acids with benzylic hydrocarbons via benzylic Csp3-H bond activation under metal-free conditions

A metal-free protocol for the direct oxidative esterification of the Csp3-H bond in benzylic hydrocarbons with carboxylic acids using heterocyclic ionic liquid as catalyst has been reported. The catalyst 1-butylpyridinium iodide could be easily recycled and reused for at least four cycles without obvious loss of catalytic activity.

Electrogenerated N-heterocyclic carbene in ionic liquid: An insight into the mechanism of the oxidative esterification of aromatic aldehydes

An N-heterocyclic carbene (NHC), generated by cathodic reduction of BMIm BF4, mediates the oxidative esterification of aromatic aldehydes with organic bromides in the corresponding ionic liquid as solvent. The product recovery by simple extractive work-up with diethyl ether allowed the ionic liquid to be recycled up to 9 times for subsequent electrolyses, with no significant loss in the product yield. The isolation of an intermediate, whose structure was confirmed by synthesis and transformation into the ester, provided the key for a mechanistic insight into the reaction.