84501-28-0

Basic information

• Product Name: 4-TERT-BUTYL-2,6-DIFORMYLPHENOL
• Synonyms: 5-(TERT-BUTYL)-2-HYDROXYISOPHTHALALDEHYDE;AKOS BC-1732;4-TERT-BUTYL-2,6-DIFORMYLPHENOL;5-(1,1-DIMETHYLETHYL)-2-HYDROXY-1,3-BENZENEDICARBOXALDEHYDE;4-tert-Butyl-2,6-diformylphenol,5-(1,1-Dimethylethyl)-2-hydroxy-1,3-benzenedicarboxaldehyde;5-(tert-Butyl)-2-hydroxybenzene-1,3-dicarboxaldehyde, 4-(tert-Butyl)-2,6-diformylphenol;4-tert-Butyl-2,6-diforMylphenol 96%;4-tert-Butyl-2,6-diformylphenol
• CAS NO: 84501-28-0
• Molecular Formula: C₁₂H₁₄O₃
• Molecular Weight: 206.24
• Product Categories: Aldehydes;Building Blocks;C10-C12;Carbonyl Compounds;Chemical Synthesis;Organic Building Blocks
• Mol File: 84501-28-0.mol
• Article Data: 22

Chemical Properties

• Melting Point: 99-103 °C(lit.)
• Boiling Point: 267.8°C at 760 mmHg
• Flash Point: 130°C
• Appearance: /
• Density: 1.159g/cm³
• Vapor Pressure: 0.00484mmHg at 25°C
• Refractive Index: 1.589
• Storage Temp.: under inert gas (nitrogen or Argon) at 2-8°C
• PKA: 6.61±0.23(Predicted)
• CAS DataBase Reference: 4-TERT-BUTYL-2,6-DIFORMYLPHENOL(CAS DataBase Reference)
• NIST Chemistry Reference: 4-TERT-BUTYL-2,6-DIFORMYLPHENOL(84501-28-0)
• EPA Substance Registry System: 4-TERT-BUTYL-2,6-DIFORMYLPHENOL(84501-28-0)

Safety Data

• Hazard Codes: Xi
• Statements: 36/37/38
• Safety Statements: 26-36
• WGK Germany: 3
• HazardClass: IRRITANT
• Hazardous Substances Data: 84501-28-0(Hazardous Substances Data)

Usage

Description

4-TERT-BUTYL-2,6-DIFORMYLPHENOL is an organic compound that serves as a key intermediate in the synthesis of various chemical compounds and sensors.

Uses

Used in Chemical Synthesis:
4-TERT-BUTYL-2,6-DIFORMYLPHENOL is used as a key intermediate for the production of a BODIPY chemodosimetric sensor for cyanide ions. This sensor is crucial for detecting and monitoring cyanide levels in various environments, ensuring safety and environmental compliance.
Used in Bimetallic Catalysis:
4-TERT-BUTYL-2,6-DIFORMYLPHENOL is also used as a Pro-ligand in bimetallic catalysis, a field of chemistry that focuses on the development of catalysts containing two or more metal atoms. These catalysts are essential for various chemical reactions and processes, improving efficiency and selectivity in the synthesis of complex molecules and materials.

InChI:InChI=1/C12H14O3/c1-12(2,3)10-4-8(6-13)11(15)9(5-10)7-14/h4-7,15H,1-3H3

Upstream product

• 50-00-0 formaldehyd 
• 98-54-4 para-tert-butylphenol 
• 100-97-0 hexamethylenetetramine 
• 94516-52-6 5-tert-butyl-1,3-bis-hydroxymethyl-2-(toluene-4-sulfonyloxy)-benzene 
• 2203-14-7 4-tert-butyl-2,5-bis(hydroxymethyl)phenol 
• 94516-53-7 Toluene-4-sulfonic acid 4-tert-butyl-2,6-diformyl-phenyl ester 

Downstream Products

• 713524-75-5 4-(tert-butyl)-2,6-diformylphenyl trifluoromethanesulfonate 
• 84501-10-0 Cu⁽²⁺⁾*((CH₃)3CC₆H₂O(CHN)(CHO))2(CH₂CH₂CH₂)^(2-) = Cu((CH₃)3CC₆H₂O(CHN)(CHO))2(CH₂CH₂CH₂) 
• 1227783-54-1 5M₅M-terbut 
• 1628570-68-2 2,6-bis[N-(2-(2-thienyl)ethyl)iminomethyl]-4-tert-butylphenol 

Relevant articles and documents

Proton-template synthesis, structure, and characterization of a Robson- type macrocycle with a totally π-conjugated system

π-Conjugated (1-4) and partially reduced (5) macrocyclic Schiff bases have been obtained by proton-template condensation of 2,6-diformyl-4-R1- phenol (R1 = Me, t-Bu) with 1,2-diamino-4,5-R2-benzene (R2 = H, Me).

Triptycene scaffolds: Synthesis and properties of triptycene-derived Schiff base compounds for the selective and sensitive detection of CN? and Cu2+

A series of triptycene-derived Schiff bases were synthesized by condensation between amino triptycenes with an appropriate aldehyde and were isolated in good to excellent (85–90%) yields. Amongst these, a triptycene-hydroxybenzaldehyde Schiff base compound proved to be a selective sensor for cyanide. It exhibited a “turn-on” fluorescence response at 490?nm to CN? facilitated by the nucleophilic addition of CN? to the aldehyde group, accompanied by a visible color change from orange to yellow. Likewise, a triptycene salicylaldehyde adduct was shown to be highly sensitive towards the detection of the CN? ion with a detection limit of 0.9?μM. On the other hand a triptycene-BODIPY Schiff base compound could be used for the detection of Cu2+ ions over other competing, biologically relevant metal ions in acetonitrile. Photophysical studies revealed a 1:1 binding model for the triptycene-BODIPY compound.

Dinucleating Ligand Platforms Supporting Indium and Zinc Catalysts for Cyclic Ester Polymerization

The synthesis of the first alkoxide-bridged indium complex supported by a chiral dinucleating ligand platform (1), along with its zinc analogue (2), is reported. Both complexes are synthesized in a one-pot reaction starting from a chiral dinucleating bis(diamino)phenolate ligand platform, sodium ethoxide, and respective metal salts. The dinucleating indium analogue (7) based on an achiral ligand backbone is also reported. Indium complexes bearing either the chiral or achiral ligand catalyze the ring-opening polymerization of racemic lactide (rac-LA) to afford highly heterotactic poly(lactic acid) (PLA; Pr > 0.85). The indium complex bearing an achiral ligand affords essentially atactic PLA from meso-LA. The role of the dinucleating ligand structure in catalyst synthesis and polymerization activity is discussed.