87184-99-4 Usage
Description
4-(TERT-BUTYLDIMETHYLSILYL)-OXY-1-BUTAN&, also known as 4-(Dimethyl-tert-Butylsilyloxy)butan-1-ol, is a colorless oil compound with the CAS number 87184-99-4. It is primarily used in organic synthesis due to its unique chemical properties.
Uses
Used in Organic Synthesis:
4-(TERT-BUTYLDIMETHYLSILYL)-OXY-1-BUTAN& is used as a synthetic intermediate for the production of various organic compounds. Its chemical properties, such as being a colorless oil, make it suitable for use in the synthesis of a wide range of organic molecules.
Used in Pharmaceutical Industry:
In the pharmaceutical industry, 4-(TERT-BUTYLDIMETHYLSILYL)-OXY-1-BUTAN& is used as a building block for the development of new drugs. Its unique structure allows it to be incorporated into the design of novel pharmaceutical compounds, potentially leading to the discovery of new therapeutic agents.
Used in Chemical Research:
4-(TERT-BUTYLDIMETHYLSILYL)-OXY-1-BUTAN& is also utilized in chemical research for studying the properties and reactions of silyl ethers. Its reactivity and stability make it an interesting subject for research in the field of organosilicon chemistry.
Overall, 4-(TERT-BUTYLDIMETHYLSILYL)-OXY-1-BUTAN& is a versatile compound with applications in various industries, including organic synthesis, pharmaceuticals, and chemical research. Its unique properties and potential for use in the development of new compounds make it an important tool in the field of chemistry.
Check Digit Verification of cas no
The CAS Registry Mumber 87184-99-4 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 8,7,1,8 and 4 respectively; the second part has 2 digits, 9 and 9 respectively.
Calculate Digit Verification of CAS Registry Number 87184-99:
(7*8)+(6*7)+(5*1)+(4*8)+(3*4)+(2*9)+(1*9)=174
174 % 10 = 4
So 87184-99-4 is a valid CAS Registry Number.
InChI:InChI=1/C10H24O2Si/c1-10(2,3)13(4,5)12-9-7-6-8-11/h11H,6-9H2,1-5H3
87184-99-4Relevant articles and documents
A mild ligand-free iron-catalyzed liberation of alcohols from allylcarbonates
Dieskau, Andre P.,Plietker, Bernd
supporting information; experimental part, p. 5544 - 5547 (2011/12/05)
Different from most carbonates the allyloxy carbonyl protecting group can be cleaved under neutral conditions using metal catalysis. However, most of the catalysts employed to date are based upon precious metals. Herein we present two protocols for the mild Fe-catalyzed liberation of alcohols from allylcarbonates that are characterized by broad functional group tolerance and exclusive chemoselectivity.
Facile cleavage of silyl protecting groups with catalytic amounts of FeCl3
Yang, Yong-Qing,Cui, Jia-Rong,Zhu, Lin-Gui,Sun, Ya-Ping,Wu, Yikang
, p. 1260 - 1262 (2007/10/03)
A very mild and environmentally benign method for removal of silyl protecting groups using catalytic amounts of iron ion in MeOH is presented. The method is particularly effective for cleaving triethylsilyl (TES) protecting groups. Georg Thieme Verlag Stuttgart.
Facile cleavage of triethylsilyl (TES) ethers using o-lodoxybenzoic acid (IBX) without affecting tert-butyldimethylsilyl (TBS) ethers
Wu, Yikang,Huang, Jia-Hui,Shen, Xin,Hu, Qi,Tang, Chao-Jun,Li, Liang
, p. 2141 - 2144 (2007/10/03)
(matrix presented) In DMSO cleavage of triethylsilyl (TES) ethers by o-iodoxybenzoic acid (IBX) was significantly faster than cleavage of tert-butyldimethylsilyl (TBS) ethers or further oxidation into carbonyl compounds. In most cases, TES protecting groups be removed in good to excellent yields within 1 h, whereas similar TBS protecting groups remained intact under the same conditions. The procedure also could be adapted for direct one-pot conversion of TES ethers into carbonyl compounds.