93629-17-5

Basic information

• Product Name: (3,5-DI-TERT-BUTYL-4-METHOXY-PHENYL)-METHANOL
• Synonyms: (3,5-DI-TERT-BUTYL-4-METHOXY-PHENYL)-METHANOL
• CAS NO: 93629-17-5
• Molecular Formula: C₁₆H₂₆O₂
• Molecular Weight: 250.37644
• Mol File: 93629-17-5.mol
• Article Data: 5

Chemical Properties

• Boiling Point: 330.3°C at 760 mmHg
• Flash Point: 121.8°C
• Appearance: /
• Density: 0.96g/cm³
• Vapor Pressure: 6.74E-05mmHg at 25°C
• Refractive Index: 1.496
• Storage Temp.: 2-8°C
• CAS DataBase Reference: (3,5-DI-TERT-BUTYL-4-METHOXY-PHENYL)-METHANOL(CAS DataBase Reference)
• NIST Chemistry Reference: (3,5-DI-TERT-BUTYL-4-METHOXY-PHENYL)-METHANOL(93629-17-5)
• EPA Substance Registry System: (3,5-DI-TERT-BUTYL-4-METHOXY-PHENYL)-METHANOL(93629-17-5)

Safety Data

• Hazardous Substances Data: 93629-17-5(Hazardous Substances Data)

Usage

Description

(3,5-DI-TERT-BUTYL-4-METHOXY-PHENYL)-METHANOL, a phenol derivative with the molecular formula C14H24O2, is a white crystalline solid at room temperature. It is insoluble in water and is commonly used as a building block in the synthesis of various organic compounds, including pharmaceuticals, agrochemicals, and other fine chemicals.

Uses

Used in Pharmaceutical Industry:
(3,5-DI-TERT-BUTYL-4-METHOXY-PHENYL)-METHANOL is used as a building block for the synthesis of pharmaceuticals, contributing to the development of new drugs and improving the efficacy and safety of existing medications.
Used in Agrochemical Industry:
(3,5-DI-TERT-BUTYL-4-METHOXY-PHENYL)-METHANOL is used as a building block for the synthesis of agrochemicals, aiding in the creation of more effective and environmentally friendly pesticides and other agricultural products.
Used in Polymer Industry:
(3,5-DI-TERT-BUTYL-4-METHOXY-PHENYL)-METHANOL is used as a stabilizer in polymers, enhancing their durability, resistance to degradation, and overall performance in various applications.
Used in Organic Reactions:
(3,5-DI-TERT-BUTYL-4-METHOXY-PHENYL)-METHANOL is used as a reagent in organic reactions, facilitating the synthesis of complex organic compounds and contributing to advancements in organic chemistry.
Safety Precautions:
(3,5-DI-TERT-BUTYL-4-METHOXY-PHENYL)-METHANOL is classified as a hazardous substance and should be handled and stored with proper safety precautions to minimize risks to human health and the environment.

InChI:InChI=1/C16H26O2/c1-15(2,3)12-8-11(10-17)9-13(14(12)18-7)16(4,5)6/h8-9,17H,10H2,1-7H3

Upstream product

• 74684-38-1 2-(3-(tert-butyl)-5-formylphenyl)-2-methylpropanenitrile 
• 1620-98-0 3,5-di-t-butyl-4-hydroxybenzaldehyde 
• 88-26-6 3,5-di-tert-butyl-4-hydroxybenzyl alcohol 
• 74-88-4 methyl iodide 
• 1516-96-7 4-bromo-2,6-di-tert-butylanisole 
• 1516-95-6 2,6-di-tert-butyl-anisole 
• 1518-53-2 1,3-di-tert-butyl-2-methoxy-5-methylbenzene 
• 128-37-0 2,6-di-tert-butyl-4-methyl-phenol 
• 93629-15-3 5-(bromomethyl)-1,3-di-tert-butyl-2-methoxybenzene 
• 74222-81-4 2-(3,5-di-tert-butyl-4-hydroxyphenyl)-1,3-dioxolane 

Downstream Products

• 845869-17-2 3,5-bis(3,5-di-tert-butyl-4-methoxybenzyloxy)benzyl alcohol 
• 845869-18-3 methyl 3,5-bis(3,5-bis(3,5-di-tert-butyl-4-methoxybenzyloxy)benzyloxy)benzoate 
• 93629-15-3 5-(bromomethyl)-1,3-di-tert-butyl-2-methoxybenzene 
• 1016636-85-3 diethyl (3,5-di-tert-butyl-4-methoxybenzyl)phosphonate 
• 1261146-15-9 (1E,3E)-1,4-bis(3,5-di-tert-butyl-4-methoxyphenyl)buta-1,3-diene 
• 32465-70-6 bis(3,5-di-tert-butyl-4-methoxyphenyl)methane 
• 1233657-21-0 C₄₀H₅₈O₆ 
• 1233657-29-8 C₄₄H₅₄N₂O₄ 
• 1233657-25-4 C₄₀H₅₄O₆ 
• 845869-16-1 methyl 3,5-bis(3,5-di-tert-butyl-4-methoxybenzyloxy)benzoate 

Relevant articles and documents

Unusual transformation of 4-hydroxy/methoxybenzylic alcohols via C[sbnd]C ipso-substitution reaction using proton-exchanged montmorillonite as media

We present here proton-exchanged montmorillonite-mediated an unusual transformation of 4-hydroxy and 4-methoxybenzylic alcohols to form symmetrical benzylic ethers and diarylmethanes under mild conditions. Nuclear magnetic resonance spectroscopy and density functional theory calculations support a plausible mechanism, which includes a distinctive aromatic C[sbnd]C ipso-substitution reaction with a hydroxymethyl group as the C-based leaving group.

Mechanistic and steric issues in the oxidation of phenolic and non-phenolic compounds by laccase or laccase-mediator systems. the case of bifunctional substrates

Steric and redox issues of phenolic and non-phenolic substrates are investigated for a better insight of the reactivity features of the phenoloxidase laccase. Whenever a substrate is endowed with a redox potential too high for direct monoelectronic oxidation by the enzyme, or else is too much encumbered to access the enzymatic pocket, redox mediators overcome the problem, behaving as an interface between enzyme and substrate. For example, the small-sized mediator ABTS, once oxidised by laccase, fruitfully interacts with bulky substrates, 2,4,6-tri(But)-phenol providing a significant case. Other mediators, for example HBT, resort to a radical oxidation mechanism precluded to laccase, and can react with non-phenolic substrates which are impossible for the enzyme. The advantages provided by the mediators are discussed, and suitable phenolic compounds, as precursors of phenoxyl radical intermediates, emerge as a new proficient class. They could be the true natural mediators of laccase in the oxidative delignification. In fact, phenoxyl radical fragments generated by laccase from lignin, or from phenolic monomer residuals from the building up of lignin polymer or else deriving from lignin by oxidation with other ligninolytic enzymes, could oxidise non-phenolic residues of lignin thereby causing the breakdown of its alkyl network. The novel mechanistic probe 3,5-di(But)-4-OH-benzyl alcohol enables the decoupling of the reactivity channels of a phenolic vs. a benzylic alcohol moiety in the enzymatic oxidation of bifunctional substrates having structural features comparable to portions of lignin. Experimental support is thereby attained for the central role of laccase in biodelignification, in spite of the seemingly lower oxidation power of this enzyme with respect to other and stronger oxidising enzymes excreted by ligninolytic fungi. the Royal Society of Chemistry and the Centre National de la Recherche Scientifique 2006.

Restricted rotation about arene-oxygen bonds in some 1,3-di-tert-butyl-2-methoxyarenedicarbonylphosphorus(III)chromium compounds

The 1H nmr spectra of 1,3-di-tert-butyl-2-methoxybenzenedicarbonyltriphenylphosphinechromium (5) and some related compounds at low temperatures show the presence of two species which interconvert with free energy of activation near 50 kJ mol-1.