944810-50-8

Basic information

• Product Name: N-benzyl-(S)-α,α-di(1-naphthyl)-2-pyrrolidinemethanol
• Synonyms: N-benzyl-(S)-α,α-di(1-naphthyl)-2-pyrrolidinemethanol
• CAS NO: 944810-50-8
• Molecular Weight: 443.588
• Mol File: 944810-50-8.mol
• Article Data: 3

Chemical Properties

• CAS DataBase Reference: N-benzyl-(S)-α,α-di(1-naphthyl)-2-pyrrolidinemethanol(CAS DataBase Reference)
• NIST Chemistry Reference: N-benzyl-(S)-α,α-di(1-naphthyl)-2-pyrrolidinemethanol(944810-50-8)
• EPA Substance Registry System: N-benzyl-(S)-α,α-di(1-naphthyl)-2-pyrrolidinemethanol(944810-50-8)

Safety Data

• Hazardous Substances Data: 944810-50-8(Hazardous Substances Data)

Upstream product

• 580-13-2 2-bromonaphthalene 
• 113304-84-0 N-benzyl-(S)-proline methyl ester 
• 703-55-9 1-naphthylmagnesiumbromide 
• 90-11-9 1-Bromonaphthalene 
• 83528-04-5 (S)-N-benzyl-O-benzylpyrrolidine-2-carboxylate 

Downstream Products

• 130798-48-0 (S)-(-)-α,α-di(2-naphthyl)-2-pyrrolidinemethanol 

Relevant articles and documents

A simple synthesis of (S)-α,α-diaryl-2-pyrrolidinemethanols

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Ligand-accelerated enantioselective propargylation of aldehydes via allenylzinc reagents

An enantioselective propargylation of aldehydes using an allenylzinc reagent generated in situ via a zinc-iodine exchange reaction is described. The enantioselectivity is controlled by addition of a catalytic amount of readily accessible and highly tunable amino alcohol ligand L13. A wide range of aldehydes can be propargylated to afford valuable and versatile homopropargyl alcohols in good to excellent yields with high levels of enantiopurity.