96-13-9 Usage
Description
2,3-Dibromo-1-propanol is an organic compound that serves as a synthetic building block, fire-proofing agent, and is recognized as a mutagen and carcinogen in experimental animals.
Uses
Used in Flame Retardant Production:
2,3-Dibromo-1-propanol is used as an intermediate in the production of flame retardants for various applications, including children's clothing and other products. It was a key component in the synthesis of tris(2,3-dibromopropyl) phosphate, a flame retardant that was banned from use in sleepwear in 1977 due to its carcinogenic properties in experimental animals.
Used in Insecticide Production:
2,3-Dibromo-1-propanol also serves as an intermediate in the production of insecticides, contributing to the development of pesticides that help control and eliminate pests.
Used in Pharmaceutical Production:
2,3-Dibromo-1-propanol is utilized as a synthetic building block in the creation of pharmaceuticals, playing a crucial role in the synthesis of various medicinal compounds.
Used as a Flame Retardant:
In addition to its role as an intermediate, 2,3-dibromo-1-propanol has been used directly as a flame retardant, providing fire-resistant properties to materials in various industries.
Synthesis Reference(s)
The Journal of Organic Chemistry, 30, p. 587, 1965 DOI: 10.1021/jo01013a069
Air & Water Reactions
Water soluble.
Reactivity Profile
2,3-Dibromo-1-propanol is incompatible with strong oxidizers.
Fire Hazard
2,3-Dibromo-1-propanol is probably combustible.
Potential Exposure
Chemical intermediate used to pro-
duce insecticides, pharmaceuticals, and flame retardants.
Carcinogenicity
2,3-Dibromo-1-propanol is reasonably anticipated to be a human carcinogen based on sufficient evidence of carcinogenicity from studies in experimental animals.
Shipping
UN2810 Toxic liquids, organic, n.o.s., Hazard
Class: 6.1; Labels: 6.1-Poisonous materials, Technical
Name Required.
Check Digit Verification of cas no
The CAS Registry Mumber 96-13-9 includes 5 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 2 digits, 9 and 6 respectively; the second part has 2 digits, 1 and 3 respectively.
Calculate Digit Verification of CAS Registry Number 96-13:
(4*9)+(3*6)+(2*1)+(1*3)=59
59 % 10 = 9
So 96-13-9 is a valid CAS Registry Number.
InChI:InChI=1/C3H6Br2O/c4-1-3(5)2-6/h3,6H,1-2H2/t3-/m0/s1
96-13-9Relevant articles and documents
-
Farkas,Schaechter
, p. 2252 (1949)
-
One-Pot Strategy for Thiazoline Synthesis from Alkenes and Thioamides
Alom, Nur-E,Wu, Fan,Li, Wei
supporting information, p. 930 - 933 (2017/02/26)
A convenient synthesis of a privileged pharmaceutical motif, thiazoline is accomplished. This reaction utilizes simple and readily available alkene and thioamide substrates in an intermolecular fashion via a simple one-pot procedure. A wide range of functional groups is tolerated, and the thiazoline product has been further utilized for the synthesis of the corresponding β-aminothiol and thiazole from routine hydrolysis and oxidation protocols.
Bromination of olefins with HBr and DMSO
Karki, Megha,Magolan, Jakob
, p. 3701 - 3707 (2015/04/22)
A simple and inexpensive methodology is reported for the conversion of alkenes to 1,2-dibromo alkanes via oxidative bromination using HBr paired with dimethyl sulfoxide, which serves as the oxidant as well as cosolvent. The substrate scope includes 21 olefins brominated in good to excellent yields. Three of six styrene derivatives yielded bromohydrins under the reaction conditions.