NOVEL COMPOUNDS WITH THYMINE SKELETON FOR USE IN MEDICINE
The present invention relates to novel compounds as new chemical entities with thymine skeleton, these compounds for use as in medicine, especially in the treatment of carcinoma, HSP27-associated diseases and cystic fibrosis; and a pharmaceutical product
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Paragraph 0123-0125; 0127
(2021/05/07)
Nonsteroidal Antiinflammatory Agents. 2. Synthesis of 4',5-Disubstituted 3-Biphenylylacetic Acids and Their Derivatives with Antiinflammatory and Analgesic Activities
A series of 4',5-disubstituted 3-biphenylylacetic acids (5a-n) and several α-methyl derivatives (5o-v) were prepared as analogues of a newly developed nonsteroidal antiinflammatory agent, 4'-chloro-5-methoxy-3-biphenylylacetic acid 1 (DKA-9), R = 4-ClPh;