2,4-Diphenylthiophene

Base Information

• Chemical Name: 2,4-Diphenylthiophene
• CAS No.: 3328-86-7
• Molecular Formula: C16H12S
• Molecular Weight: 236.337
• Hs Code.: 2934999090
• Mol file: 3328-86-7.mol

Synonyms:2,4-Diphenyl-thiophen;Thiophene, 2,4-diphenyl-;Thiophene,2,4-diphenyl;2,4-diphenyl-thiophene;

Chemical Property of 2,4-Diphenylthiophene

Chemical Property:

• Melting Point: 122.5 °C(Solv: ethanol (64-17-5))
• Boiling Point: 260-265 °C(Press: 36 Torr)
• PSA: 28.24000
• Density: 1.128±0.06 g/cm3(Predicted)
• LogP: 5.08210

Purity/Quality:

95% ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 2,4-Diphenylthiophene

There total 97 articles about 2,4-Diphenylthiophene which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 100.0%

N-(3,5-diphenyl-2-thenoyl)aniline (437606-43-4) → 2,4-diphenylthiophene (3328-86-7)

Guidance literature:

With palladium diacetate; P(O-biphenyl)(t-Bu)2; caesium carbonate; In o-xylene; for 24h; Heating;

DOI:10.1021/ja0259279

Reference yield: 86.0%

2-phenylthiophene (825-55-8) + phenylboronic acid (98-80-6) → 2,4-diphenylthiophene (3328-86-7)

Guidance literature:

With palladium(II) trifluoroacetate; cesium trifluoroacetate; p-benzoquinone; silver(l) oxide; In acetic acid; trifluoroacetic acid; at 20 ℃; for 15h; regioselective reaction;

DOI:10.1002/chem.201503067

Reference yield: 80.0%

phenylacetylene (536-74-3) → 2,4-diphenylthiophene (3328-86-7)

Guidance literature:

With hydrogen sulfide; sulfur; In various solvent(s); at 170 ℃; for 5h;

upstream raw materials:

styrene

methyl magnesium iodide

dihydrochalcone

2,5-diphenyl-[1,4]dithiine

Downstream raw materials:

2,3,5-triphenylthiophene

3,5-diphenyl-thiophene-2-carboxylic acid

Refernces

• 1、 Fernandes, Rushil,Mhaske, Krishna,Narayan, Rishikesh. "β-Bromoenol phosphate as a new precursor for the modular regioselective synthesis of substituted furans". supporting information. . Retrieved 2021/11/24.
• 2、 Nguyen, Thanh Binh,Retailleau, Pascal. "Sulfurative self-condensation of ketones and elemental sulfur: A three-component access to thiophenes catalyzed by aniline acid-base conjugate pairs". . p. 387 - 390. Retrieved 2018/02/07.