BLASTICIDIN S

Base Information Edit

Chemical Name:BLASTICIDIN S
CAS No.:2079-00-7
Deprecated CAS:11002-92-9,11028-10-7,12767-55-4,13184-51-5,7562-21-2
Molecular Formula:C₁₇H₂₆N₈O₅
Molecular Weight:422.444
Hs Code.:29349990
European Community (EC) Number:606-640-2
ICSC Number:1758
UN Number:2588
UNII:83U64J9U23
Wikipedia:Blasticidin_S
ChEMBL ID:CHEMBL511116
Mol file:2079-00-7.mol

Synonyms:BlasticidinS (6CI,8CI);D-erythro-Hex-2-enopyranuronic acid,4-[3-amino-5-(1-methylguanidino)valeramido]-1-(4-amino-2-oxo-1(2H)-pyrimidinyl)-1,2,3,4-tetradeoxy-(7CI);Bla-S;

Suppliers and Price of BLASTICIDIN S

Supply Marketing:Edit

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

American Custom Chemicals Corporation
BLASTICIDIN S 95.00%
50MG
$ 759.41

American Custom Chemicals Corporation
BLASTICIDIN S 95.00%
250MG
$ 1086.86

American Custom Chemicals Corporation
BLASTICIDIN S 95.00%
100MG
$ 839.45

AHH
BlasticidinS 98%
0.5g
$ 770.00

Total 7 raw suppliers

Chemical Property of BLASTICIDIN S Edit

Chemical Property:

Appearance/Colour:Colourless needles
Vapor Pressure:Low
Melting Point:235-236ºC
Refractive Index:1.707
Boiling Point:°Cat760mmHg
PKA:2.4 (carboxyl), 4.6,8.0 and>12.5 (three bases)
Flash Point:°C
PSA：215.67000
Density:1.61 g/cm³
LogP:0.25370
Water Solubility.:>30 g l-1(20 °C)
XLogP3:-5.2
Hydrogen Bond Donor Count:6
Hydrogen Bond Acceptor Count:7
Rotatable Bond Count:9
Exact Mass:422.20261596
Heavy Atom Count:30
Complexity:795

Purity/Quality:

98%, ^*data from raw suppliers

BLASTICIDIN S 95.00% ^*data from reagent suppliers

Safty Information:

Pictogram(s): T+
Hazard Codes:T+
Statements: 28
Safety Statements: 24/25-36/37-45

MSDS Files:: Total 1 MSDS from other Authors

Useful:

Chemical Classes:Pesticides -> Fungicides
Canonical SMILES:CN(CCC(CC(=O)NC1C=CC(OC1C(=O)O)N2C=CC(=NC2=O)N)N)C(=N)N
Isomeric SMILES:CN(CC[C@@H](CC(=O)N[C@@H]1C=C[C@H](O[C@H]1C(=O)O)N2C=CC(=NC2=O)N)N)C(=N)N
Inhalation Risk:A harmful concentration of airborne particles can be reached quickly when dispersed, especially if powdered.
Effects of Short Term Exposure:The substance is severely irritating to the eyes. The substance is irritating to the respiratory tract and skin. Corrosive on ingestion. Exposure at high levels could cause death.
Description Nucleoside antibiotic produced by Streptomyces griseochromogenes (1). Biosynthesized from cytosine, glucose, arginine, and methionine (2).
Uses Blasticidin S is a nucleoside produced by several species of Streptomyces, first reported in the late 1950s. Blasticidin S is an antifungal agent with particularly potent activity against the rice pathogen, Piricularia oryzae, for which it was used commercially for some time in Japan. Blasticidin S inhibits protein synthesis and is active against bacteria, tumour cell lines and nematodes. More recently, blasticidin S has been used as a marker for strain manipulations. Blasticidin S provided by BioAustralis is presented as the free base to avoid problems associated with the use of the hydrochloride. Blasticidin-S is used for the control of rice blast (PyricuZuria oryzae) by foliar application.

Technology Process of BLASTICIDIN S

There total 6 articles about BLASTICIDIN S which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 19018-47-4
leucylblasticidin S

: 2079-00-7
(+)-blasticidin S

Guidance literature:: With Streptomyces griseochromogenes cell-free extract; In phosphate buffer; at 30 ℃; pH=7.0; Enzymatic reaction;
DOI:10.1016/S0040-4020(99)01060-1