Daturabietatriene

Base Information

• Chemical Name: Daturabietatriene
• CAS No.: 65894-41-9
• Molecular Formula: C20H30O2
• Molecular Weight: 302.45
• Mol file: 65894-41-9.mol

Synonyms:11,13-trien-15-amine,13-isopropyl-podocarpa-acetate;Rosin amine D acetate;DELRAD;DEHYDROABIETYLAMINE ACETATE,TECH.;8,11,13-abietatriene-15,18-diol;daturabietatriene;15,18-dihydroxyabieta-8,11,13-triene;abieta-8,11,13-trien-18-ylamine,acetate;Abieta-8,11,13-trien-18-ylamin,Acetat;Podocarpa-8,11,13-trien-15-amine,13-isopropyl-,acetate;

Chemical Property of Daturabietatriene

Chemical Property:

• PSA: 40.46000
• LogP: 3.91660

Purity/Quality:

98%min ^*data from raw suppliers

Daturabietatriene 95+% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of Daturabietatriene

There total 9 articles about Daturabietatriene which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 95.0%

15-hydroxydehydroabietic acid methyl ester (29461-23-2) → abieta-8,11,13-triene-15,18-diol (65894-41-9)

Guidance literature:

With lithium aluminium tetrahydride; In tetrahydrofuran; at 20 ℃; for 12h;

DOI:10.1016/j.tetlet.2006.02.037

Reference yield: 84.0%

ethyl 15-hydroxydehydroabietate → abieta-8,11,13-triene-15,18-diol (65894-41-9)

Guidance literature:

With lithium aluminium tetrahydride; In tetrahydrofuran; at 20 ℃; for 3h;

Reference yield:

abietic acid (514-10-3) → abieta-8,11,13-triene-15,18-diol (65894-41-9)

Guidance literature:

Multi-step reaction with 5 steps

1.1: hydrogen bromide; acetic acid / 6 h / 20 °C

2.1: lithium hydroxide / N,N-dimethyl-formamide / 7 h / 80 °C

3.1: selenium(IV) oxide / tetrahydrofuran / 5 h / 0 °C

4.1: potassium carbonate / 0.25 h / 20 °C

4.2: 3 h / 60 °C

5.1: lithium aluminium tetrahydride / tetrahydrofuran / 3 h / 20 °C

With selenium(IV) oxide; lithium aluminium tetrahydride; hydrogen bromide; potassium carbonate; acetic acid; lithium hydroxide; In tetrahydrofuran; N,N-dimethyl-formamide;

upstream raw materials:

15-hydroxydehydroabietic acid methyl ester

abieta-8,13⁽¹⁵⁾-dien-18-oic acid

methyl abieta-8,13⁽¹⁵⁾-dien-18-oate

abietic acid

Refernces

• 1、 -. "Preparation method of 15-hydroxyl dehydrogenated abietane and intermediate of 15-hydroxyl dehydrogenated abietane". . . Retrieved 2017/08/29.
• 2、 Alvarez-Manzaneda,Chahboun,Guardia,Lachkar,Dahdouh,Lara,Messouri. "New route to 15-hydroxydehydroabietic acid derivatives: Application to the first synthesis of some bioactive abietane and nor-abietane type terpenoids". . p. 2577 - 2580. Retrieved 2007/10/03.