mupinensisone

Base Information

• Chemical Name: mupinensisone
• CAS No.: 152253-67-3
• Molecular Formula: C₃₀H₄₈O₂
• Molecular Weight: 440.71
• Mol file: 152253-67-3.mol

Synonyms:Mupinensisone

Chemical Property of mupinensisone

Chemical Property:

• Vapor Pressure: 4.12E-13mmHg at 25°C
• Boiling Point: 522.7°Cat760mmHg
• PKA: 15.04±0.10(Predicted)
• Flash Point: 220.8°C
• PSA: 37.30000
• Density: 1.05g/cm³
• LogP: 7.34950

Purity/Quality:

98% ^*data from raw suppliers

Mupinensisone ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of mupinensisone

There total 2 articles about mupinensisone which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

11-hydroxymethyl-4,4a,6a,6b,8a,11,14b-heptamethyl-1,2,3,4,4a,5,6,6a,6b,7,8,8a,9,10,11,12,12a,14,14a,14b-eicosahydropicen-3-ol (6813-59-8) → olean-3-oxo-12-en-30-ol (152253-67-3) + olean-12-ene-3β,7β,15α,30-tetraol + olean-12-ene-3β,7β,11α,15α,30-pentol + olean-12-ene-3β,7β,15α,19α,30-pentol + olean-12-ene-3β,7β,15α,27,30-pentol + olean-9(11),12(13)-diene-3β,7β,15α,27,30-pentol + 3β,7β,11α,30-tetrahydroxy-olean-12-en-27-aldehyde

Guidance literature:

With hydrogenchloride; dipotassium hydrogenphosphate; D-glucose; water; sodium chloride; In acetone; at 121 ℃; for 96h; stereoselective reaction; Microbiological reaction; Autoclave;

DOI:10.1016/j.bmc.2020.115465

Reference yield:

enoxolone (471-53-4) → olean-3-oxo-12-en-30-ol (152253-67-3) + olean-12-ene-3β,7β,15α,30-tetraol + olean-12-ene-3β,7β,11α,15α,30-pentol + olean-12-ene-3β,7β,15α,19α,30-pentol + olean-12-ene-3β,7β,15α,27,30-pentol + olean-9(11),12(13)-diene-3β,7β,15α,27,30-pentol + 3β,7β,11α,30-tetrahydroxy-olean-12-en-27-aldehyde

Guidance literature:

Multi-step reaction with 3 steps

1: zinc amalgam; hydrogenchloride

2: lithium aluminium tetrahydride / tetrahydrofuran / 60 °C

3: hydrogenchloride; D-glucose; sodium chloride; dipotassium hydrogenphosphate; water / acetone / 96 h / 121 °C / Microbiological reaction; Autoclave

With hydrogenchloride; dipotassium hydrogenphosphate; lithium aluminium tetrahydride; D-glucose; zinc amalgam; water; sodium chloride; In tetrahydrofuran; acetone; 1: |Clemmensen Reduction;

DOI:10.1016/j.bmc.2020.115465

upstream raw materials:

enoxolone

11-hydroxymethyl-4,4a,6a,6b,8a,11,14b-heptamethyl-1,2,3,4,4a,5,6,6a,6b,7,8,8a,9,10,11,12,12a,14,14a,14b-eicosahydropicen-3-ol

Refernces