Stylomycin dihydrochloride

Base Information

• Chemical Name: Stylomycin dihydrochloride
• CAS No.: 58-58-2
• Molecular Formula: C22H29 N7 O5 . 2 Cl H
• Molecular Weight: 544.438
• Hs Code.: 29419090
• European Community (EC) Number: 200-387-8
• Mol file: 58-58-2.mol

Synonyms:P 638 dihydrochloride;Stylomycin dihydrochloride;3123L, dihydrochloride;CL 13,900 dihydrochloride;C22H29N7O5.2ClH;Puromycin hydrochloride [USAN];EINECS 200-387-8;C22-H29-N7-O5.2Cl-H;CL16,536;Prestwick_627;AI3-26818;X 185;3'-(L-alpha-Amino-p-methoxyhydrocinnamamido)-3'-deoxy-N,N-dimethyladenosine dihydrochloride;HMS1569O22;(S)-3'-[[2-amino-3-(4-methoxyphenyl)-1-oxopropyl]amino]-3'-deoxy-N,N-dimethyladenosindihydrochlorid;(S)-3'-[[2-amino-3-(4-methoxyphenyl)-1-oxopropyl]amino]-3'-deoxy-N,N-dimethyladenosine dihydrochloride

Chemical Property of Stylomycin dihydrochloride

Chemical Property:

• Appearance/Colour: white powder
• Melting Point: 168-170℃
• Boiling Point: °Cat760mmHg
• Flash Point: °C
• PSA: 160.88000
• Density: g/cm³
• LogP: 1.09950
• Storage Temp.: −20°C
• Solubility.: H2O: soluble50mg/mL (Sterilize stock solution by filtration usin
• Water Solubility.: Soluble in water
• Hydrogen Bond Donor Count: 6
• Hydrogen Bond Acceptor Count: 10
• Rotatable Bond Count: 8
• Exact Mass: 543.1763725
• Heavy Atom Count: 36
• Complexity: 680

Purity/Quality:

98%, ^*data from raw suppliers

Puromycin Dihydrochloride ^*data from reagent suppliers

Safty Information:

• Pictogram(s): Xn
• Hazard Codes: Xn
• Statements: 22-40
• Safety Statements: 24/25

MSDS Files:

SDS file from LookChem

Total 1 MSDS from other Authors

Useful:

• Canonical SMILES: CN(C)C1=NC=NC2=C1N=CN2C3C(C(C(O3)CO)NC(=O)C(CC4=CC=C(C=C4)OC)N)O.Cl.Cl
• Isomeric SMILES: CN(C)C1=NC=NC2=C1N=CN2[C@H]3C([C@H]([C@H](O3)CO)NC(=O)C(CC4=CC=C(C=C4)OC)N)O.Cl.Cl
• Description: Puromycin (58-58-2) is an aminonucleoside antibiotic derived from Streptomyces alboniger. It is a protein synthesis inhibitor that disrupts peptide transfer on ribosomes causing premature chain termination.1 It is an inhibitor of dipeptidyl-peptidase II and cytosolic alanyl aminopeptidase.2 Puromycin also inhibits protein transport in mitochondria.3
• Uses: Puromycin is an aminonucleoside antibitotic. Puromycin acts as a protein synthesis inhibitor which interferes with translation by inhibiting ribosome functions. Puromycin is also a reversible inhibitor of dipeptidyl-peptidase II (serine peptidase) and cytosol alanyl aminopeptidase. antibacterial Puromycin dihydrochloride is the salt of puromycin, a nucleoside antibiotic isolated from Streptomyces alboniger in the 1950s as an anti-trypansomal agent with antibiotic activity. While the salt shares the same pharmacological properties as puromycin free base, its greater water solubility offers advantages in some in vitro applications. Physicochemical properties and chromatographic behaviour will depend on whether the pH is buffered. In non-pH controlled systems, the free base and salt may behave differently. Puromycin dihydrochloride is a salt of puromycin, a nucleoside antibiotic isolated from Streptomyces alboniger in the 1950s as an anti-trypansomal agent with antibiotic activity. While the salt shares the same pharmacological properties as puromycin free base, its greater water solubility offers advantages in some in vitro applications. Physicochemical properties and chromatographic behaviour will depend on whether the pH is buffered. In non-pH controlled systems, the free base and salt may behave differently. An aminonuclease antibiotic used for selection and maintenance of cell lines expressing a transfected pac gene. Research tool for studying protein synthesis; cell line selection agent in gene transfer experiments.