DIMETHYLETHANOLAMINESUCCINATE

Base Information

• Chemical Name: DIMETHYLETHANOLAMINESUCCINATE
• CAS No.: 10549-59-4
• Molecular Formula: C8H15 N O4
• Molecular Weight: 189.21
• Hs Code.: 2924199090
• Mol file: 10549-59-4.mol

Synonyms:Butanedioicacid, mono[2-(dimethylamino)ethyl] ester (9CI); Ethanol, 2-dimethylamino-,succinate (6CI); Succinic acid, 2-(dimethylamino)ethyl ester (7CI); Succinicacid, mono[2-(dimethylamino)ethyl] ester (8CI); Mono[2-(dimethylamino)ethyl]succinate; Tonibral

Chemical Property of DIMETHYLETHANOLAMINESUCCINATE

Chemical Property:

• Melting Point: 78℃
• PSA: 98.07000
• LogP: -0.52390
• Storage Temp.: -20°C Freezer, Under inert atmosphere
• Solubility.: Methanol

Purity/Quality:

98%,99%, ^*data from raw suppliers

Tonibral ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Uses: Tonibral is an intermediate in the synthesis of Succinyl Monocholine Iodide (S688840). Succinyl Monocholine Chloride is a reagent in the synthesis of novel amphiphillic conjugates with the ability to recognize signals and exist as targeted liposomal delivery systems.

Technology Process of DIMETHYLETHANOLAMINESUCCINATE

There total 2 articles about DIMETHYLETHANOLAMINESUCCINATE which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

succinic acid anhydride (108-30-5) + 2-(N,N-dimethylamino)ethanol (108-01-0) → DMAE succinate (10549-59-4)

Guidance literature:

With acetone;

DOI:10.1021/ja01115a032

Reference yield:

→ DMAE succinate (10549-59-4)

Guidance literature:

Bernsteinsaeureanhydrid, SOCl2, 2-(Dimethylamino)aethanol;

Reference yield:

DMAE succinate (10549-59-4) + OH-[G2]-PGLSA-TBDPS (455281-63-7) → Dimethylamino-[G2]-PGLSA-TBDPS dendron

Guidance literature:

With dicyclohexyl-carbodiimide; 4-(dimethylamino)pyridinium tosylate; In tetrahydrofuran; at 20 ℃; for 14h;

upstream raw materials:

succinic acid anhydride

2-(N,N-dimethylamino)ethanol

Refernces

• 1、 Philips. "-". . p. 4725. Retrieved 1953.