[(6E,10E,14E,18E)-13-(1-ethoxyethoxy)-2,6,10,15,19,23-hexamethyltetracosa-2,6,10,14,18,22-hexaen-12-yl]sulfonylbenzene

Base Information

• Chemical Name: [(6E,10E,14E,18E)-13-(1-ethoxyethoxy)-2,6,10,15,19,23-hexamethyltetracosa-2,6,10,14,18,22-hexaen-12-yl]sulfonylbenzene
• CAS No.: 1299297-72-5
• Molecular Formula: C₄₀H₆₂O₄S
• Molecular Weight: 638.996
• Mol file: 1299297-72-5.mol

Synonyms:[(6E,10E,14E,18E)-13-(1-ethoxyethoxy)-2,6,10,15,19,23-hexamethyltetracosa-2,6,10,14,18,22-hexaen-12-yl]sulfonylbenzene

Chemical Property of [(6E,10E,14E,18E)-13-(1-ethoxyethoxy)-2,6,10,15,19,23-hexamethyltetracosa-2,6,10,14,18,22-hexaen-12-yl]sulfonylbenzene

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of [(6E,10E,14E,18E)-13-(1-ethoxyethoxy)-2,6,10,15,19,23-hexamethyltetracosa-2,6,10,14,18,22-hexaen-12-yl]sulfonylbenzene

There total 3 articles about [(6E,10E,14E,18E)-13-(1-ethoxyethoxy)-2,6,10,15,19,23-hexamethyltetracosa-2,6,10,14,18,22-hexaen-12-yl]sulfonylbenzene which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 90.0%

(6E,10E,14E,18E)-2,6,10,15,19,23-hexamethyl-13-(phenylsulfonyl)tetracosa-2,6,10,14,18,22-hexaen-12-ol + ethyl vinyl ether (109-92-2,25104-37-4) → [(6E,10E,14E,18E)-13-(1-ethoxyethoxy)-2,6,10,15,19,23-hexamethyltetracosa-2,6,10,14,18,22-hexaen-12-yl]sulfonylbenzene (1299297-72-5)

Guidance literature:

With pyridinium p-toluenesulfonate; In dichloromethane; at 0 ℃; for 2h; Inert atmosphere;

DOI:10.1021/ol200779y

Reference yield:

Farnesal (502-67-0) → [(6E,10E,14E,18E)-13-(1-ethoxyethoxy)-2,6,10,15,19,23-hexamethyltetracosa-2,6,10,14,18,22-hexaen-12-yl]sulfonylbenzene (1299297-72-5)

Guidance literature:

Multi-step reaction with 2 steps

1.1: n-butyllithium / tetrahydrofuran; hexane / 1 h / -78 °C / Inert atmosphere

1.2: 2 h / -78 °C / Inert atmosphere

2.1: pyridinium p-toluenesulfonate / dichloromethane / 2 h / 0 °C / Inert atmosphere

With n-butyllithium; pyridinium p-toluenesulfonate; In tetrahydrofuran; hexane; dichloromethane;

DOI:10.1021/ol200779y

Reference yield:

(E,E)-farnesyl phenylsulfone (56881-53-9) → [(6E,10E,14E,18E)-13-(1-ethoxyethoxy)-2,6,10,15,19,23-hexamethyltetracosa-2,6,10,14,18,22-hexaen-12-yl]sulfonylbenzene (1299297-72-5)

Guidance literature:

Multi-step reaction with 2 steps

1.1: n-butyllithium / tetrahydrofuran; hexane / 1 h / -78 °C / Inert atmosphere

1.2: 2 h / -78 °C / Inert atmosphere

2.1: pyridinium p-toluenesulfonate / dichloromethane / 2 h / 0 °C / Inert atmosphere

With n-butyllithium; pyridinium p-toluenesulfonate; In tetrahydrofuran; hexane; dichloromethane;

DOI:10.1021/ol200779y

upstream raw materials:

Farnesal

(E,E)-farnesyl phenylsulfone

ethyl vinyl ether

Downstream raw materials:

2,6,10,15,19,23-hexamethyltetracosa-2,6,10,14,18,22-hexaene

Refernces