6t-(4-hydroxy-3-methoxy-phenyl)-4-oxo-hex-5-enoic acid

Base Information

• Chemical Name: 6t-(4-hydroxy-3-methoxy-phenyl)-4-oxo-hex-5-enoic acid
• CAS No.: 69662-24-4
• Molecular Formula: C₁₃H₁₄O₅
• Molecular Weight: 250.251
• Mol file: 69662-24-4.mol

Synonyms:6t-(4-hydroxy-3-methoxy-phenyl)-4-oxo-hex-5-enoic acid

Chemical Property of 6t-(4-hydroxy-3-methoxy-phenyl)-4-oxo-hex-5-enoic acid

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 6t-(4-hydroxy-3-methoxy-phenyl)-4-oxo-hex-5-enoic acid

There total 2 articles about 6t-(4-hydroxy-3-methoxy-phenyl)-4-oxo-hex-5-enoic acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 57.0%

vanillin (121-33-5,8014-42-4) + levulinic acid (123-76-2) → 6t-(4-hydroxy-3-methoxy-phenyl)-4-oxo-hex-5-enoic acid (69662-24-4)

Guidance literature:

With pyrrolidine; acetic acid; In toluene; at 40 - 140 ℃; for 3h; Reagent/catalyst; Inert atmosphere; Dean-Stark; Green chemistry;

DOI:10.1002/cctc.201801381

Reference yield:

→ 6t-(4-hydroxy-3-methoxy-phenyl)-4-oxo-hex-5-enoic acid (69662-24-4)

Guidance literature:

/BRN= 3147080/;

Reference yield: 66.0%

6t-(4-hydroxy-3-methoxy-phenyl)-4-oxo-hex-5-enoic acid (69662-24-4) → C13H16O5 + 5-[2-(4-Hydroxy-3-methoxy-phenyl)-ethyl]-dihydro-furan-2-one

Guidance literature:

With palladium 10% on activated carbon; hydrogen; at 20 ℃; for 2h; under 760.051 Torr; Reagent/catalyst; Temperature;

DOI:10.1002/cctc.201801381

upstream raw materials:

vanillin

levulinic acid

Refernces