(2,6-dimethylphenyl)phosphonous chloride diehylamide

Base Information

• Chemical Name: (2,6-dimethylphenyl)phosphonous chloride diehylamide
• CAS No.: 85320-26-9
• Molecular Formula: C₁₂H₁₉ClNP
• Molecular Weight: 243.716
• Mol file: 85320-26-9.mol

Synonyms:(2,6-dimethylphenyl)phosphonous chloride diehylamide

Chemical Property of (2,6-dimethylphenyl)phosphonous chloride diehylamide

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of (2,6-dimethylphenyl)phosphonous chloride diehylamide

There total 2 articles about (2,6-dimethylphenyl)phosphonous chloride diehylamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 87.0%

bis(diethylamino)-2,6-dimethylphenylphosphine (6782-01-0) → (2,6-dimethylphenyl)phosphonous chloride diehylamide (85320-26-9)

Guidance literature:

With phosphorus trichloride; In diethyl ether; for 3h;

DOI:10.1016/S0040-4020(01)91106-8

Reference yield:

2-Bromo-m-xylene (576-22-7) → (2,6-dimethylphenyl)phosphonous chloride diehylamide (85320-26-9)

Guidance literature:

Multi-step reaction with 2 steps

1: 1.) THF, 2.) -55 deg C to -70 deg C, 2h, RT, 20h, THF

2: 87 percent / PCl₃ / diethyl ether / 3 h

With phosphorus trichloride; In diethyl ether;

DOI:10.1016/S0040-4020(01)91106-8

Reference yield: 89.0%

ethanol (64-17-5) + (2,6-dimethylphenyl)phosphonous chloride diehylamide (85320-26-9) → ethyl (2,6-dimethylphenyl)phosphonous diehylamide (85320-27-0)

Guidance literature:

With triethylamine; for 24h;

DOI:10.1021/ja00350a047

upstream raw materials:

bis(diethylamino)-2,6-dimethylphenylphosphine

2-Bromo-m-xylene

Downstream raw materials:

ethyl (2,6-dimethylphenyl)phosphonous diehylamide

diethylamino(diphenylmethyl)-2,6-dimethylphenylphosphine

(Diethylamino)(2,6-dimethylphenyl)(9-fluorenyl)phosphan

ethyl (2,6-dimethylphenyl)thiophosphinate

Refernces