HEPTAKIS-6-IODO-6-DEOXY-BETA-CYCLODEXTRIN

Base Information

• Chemical Name: HEPTAKIS-6-IODO-6-DEOXY-BETA-CYCLODEXTRIN
• CAS No.: 30754-23-5
• Molecular Formula: C42H63 I7 O28
• Molecular Weight: 1904.28
• Hs Code.: 29400000
• Mol file: 30754-23-5.mol

Synonyms:b-Cyclodextrin,6,6',6'',6''',6'''',6''''',6''''''-heptadeoxy-6,6',6'',6''',6'''',6''''',6''''''-heptaiodo-(8CI);2,4,7,9,12,14,17,19,22,24,27,29,32,34-Tetradecaoxaoctacyclo[31.2.2.23,6.28,11.213,16.218,21.223,26.228,31]nonatetracontane,b-cyclodextrin deriv.;Heptakis(6-deoxy-6-iodo)-b-cyclodextrin; Heptakis(6-deoxy-6-iodo)cyclomaltoheptaose;Heptakis(6-iodo-6-deoxy)-b-cyclodextrin; Per-6-iodo-b-cyclodextrin

Chemical Property of HEPTAKIS-6-IODO-6-DEOXY-BETA-CYCLODEXTRIN

Chemical Property:

• Melting Point: 218-222 °C
• Boiling Point: 1541.4±60.0 °C(Predicted)
• PKA: 11?+-.0.70(Predicted)
• PSA: 412.44000
• Density: 2.245±0.06 g/cm3(Predicted)
• LogP: -5.13170
• Solubility.: Soluble in DMF, DMSO.Insoluble in water, methanol, chloroform.

Purity/Quality:

98%min ^*data from raw suppliers

Heptakis(6-iodo-6-deoxy)-β-cyclodextrin 97% ^*data from reagent suppliers

Safty Information:

• Safety Statements: 24/25

MSDS Files:

SDS file from LookChem

Useful:

• Uses: Per-6-iodo-β-cyclodextrin is useful in perthiocyclodextrin preparation.

Technology Process of HEPTAKIS-6-IODO-6-DEOXY-BETA-CYCLODEXTRIN

There total 1 articles about HEPTAKIS-6-IODO-6-DEOXY-BETA-CYCLODEXTRIN which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 92.0%

β‐cyclodextrin (7585-39-9) → heptakis(6-deoxy-6-iodo)cyclomaltoheptaose (30754-23-5)

Guidance literature:

With iodine; triphenylphosphine; In N,N-dimethyl-formamide; at 70 ℃; for 18h;

DOI:10.1021/jo951396d

Reference yield: 100.0%

heptakis(6-deoxy-6-iodo)cyclomaltoheptaose (30754-23-5) → heptakis-6-azido-6-deoxy-beta-cyclodextrin (53958-47-7)

Guidance literature:

With sodium azide; In N,N-dimethyl-formamide;

DOI:10.1016/j.bmc.2005.07.054

Reference yield: 81.0%

heptakis(6-deoxy-6-iodo)cyclomaltoheptaose (30754-23-5) → heptakis-(6-mercapto-6-deoxy)-β-cyclodextrin (160661-60-9)

Guidance literature:

heptakis(6-deoxy-6-iodo)cyclomaltoheptaose; With thiourea; In N,N-dimethyl-formamide; at 70 ℃; for 19h; Inert atmosphere;

With water; sodium hydroxide; for 1h; Reflux;

DOI:10.1039/c2cc33742h

upstream raw materials:

β‐cyclodextrin

Downstream raw materials:

heptakis-6-azido-6-deoxy-beta-cyclodextrin

per-6-(p-tolylamino)-β-cyclodextrin

heptakis-(6-mercapto-6-deoxy)-β-cyclodextrin

4-formylphenyl (3r,5r,7r)-adamantane-1-carboxylate

Refernces

• 1、 Roehri-Stoeckel, Christine,Dangles, Olivier,Brouillard, Raymond. "A simple synthesis of a highly water soluble symmetrical β-cyclodextrin derivative". . p. 1551 - 1554. Retrieved 1997.
• 2、 Wang, Ting,Wang, Mingdong,Ding, Chendi,Fu, Jiajun. "Mono-benzimidazole functionalized β-cyclodextrins as supramolecular nanovalves for pH-triggered release of p-coumaric acid". . p. 12469 - 12472. Retrieved 2014.
• 3、 Shi, Yuting,Li, Hongping,Cheng, Ju,Luan, Tingting,Liu, Di,Cao, Yufei,Zhang, Xiangdong,Wei, Hua,Liu, Yali,Zhao, Guanghui. "Entirely oligosaccharide-based supramolecular amphiphiles constructed: Via host-guest interactions as efficient drug delivery platforms". . p. 12302 - 12305. Retrieved 2017.
• 4、 Chen, Changhui,Chen, Yong,Dai, Xianyin,Li, Jingjing,Jia, Shanshan,Wang, Shuaipeng,Liu, Yu. "Multicharge β-cyclodextrin supramolecular assembly for ATP capture and drug release". . p. 2812 - 2815. Retrieved 2021.
• 5、 Bavireddi, Harikrishna,Bharate, Priya,Kikkeri, Raghavendra. "Probing carbohydrate-carbohydrate interactions by photoswitchable supramolecular glycoclusters". . p. 3988 - 3990. Retrieved 2013.
• 6、 El Ghoul, Yassine,Renia, Ruddy,Faye, Ibrahima,Rassou, Soumassoudrane,Badi, Nezha,Bennevault-Celton, Veronique,Huin, Cecile,Guegan, Philippe. "Biomimetic artificial ion channels based on beta-cyclodextrin". . p. 11647 - 11649. Retrieved 2013.
• 7、 Chen, Pu-Guang,Huang, Zhi-Hua,Sun, Zhan-Yi,Li, Qian-Qian,Chen, Yong-Xiang,Zhao, Yu-Fen,Li, Yan-Mei. "Synthesis of an MUC1 Glycopeptide Dendrimer Based on β-Cyclodextrin by Click Chemistry". . p. 1961 - 1965. Retrieved 2017.
• 8、 -. "Method for synthesizing beta-hydroxy carbonyl compound by catalyzing asymmetric Aldol reaction in water phase". Paragraph 0032-0033. . Retrieved 2021/01/28.