2-(2,5-Dichlorophenyl)ethan-1-ol

Base Information

• Chemical Name: 2-(2,5-Dichlorophenyl)ethan-1-ol
• CAS No.: 1875-87-2
• Molecular Formula: C₈H₈Cl₂O
• Molecular Weight: 191.057
• Hs Code.: 2906290090
• European Community (EC) Number: 898-070-8
• DSSTox Substance ID: DTXSID40541841
• Wikidata: Q72467394
• Mol file: 1875-87-2.mol

Synonyms:1875-87-2;2-(2,5-Dichlorophenyl)ethan-1-ol;2-(2,5-Dichlorophenyl)ethanol;2,5-DICHLOROPHENETHYL ALCOHOL;2,5-dichloroBenzeneethanol;CK1134;2,5-Dichlorphenylmethylcarbinol;SCHEMBL1560923;DTXSID40541841;MFCD04038828;AKOS012084730;AB93008;AS-19435;2,5-dichlorophenethyl alcohol, AldrichCPR;2-(2 pound not5-Dichlorophenyl)ethan-1-ol;CS-0157666;EN300-1231465;A880572

Chemical Property of 2-(2,5-Dichlorophenyl)ethan-1-ol

Chemical Property:

• Melting Point: 26-28℃
• Boiling Point: 274℃
• Flash Point: 117℃
• Density: 1.329
• Storage Temp.: Sealed in dry,Room Temperature
• XLogP3: 2.8
• Hydrogen Bond Donor Count: 1
• Hydrogen Bond Acceptor Count: 1
• Rotatable Bond Count: 2
• Exact Mass: 189.9952203
• Heavy Atom Count: 11
• Complexity: 119

Purity/Quality:

98%,99%, ^*data from raw suppliers

2-(2,5-Dichlorophenyl)ethan-1-ol 97% ^*data from reagent suppliers

Safty Information:

• Hazard Codes: Xn
• Statements: 22

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: C1=CC(=C(C=C1Cl)CCO)Cl

Technology Process of 2-(2,5-Dichlorophenyl)ethan-1-ol

There total 3 articles about 2-(2,5-Dichlorophenyl)ethan-1-ol which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 98.8%

methyl 2-(2,5-dichlorophenyl)acetate (96129-66-7) → 2,5-dichloro-β-phenethyl alcohol (1875-87-2)

Guidance literature:

With lithium aluminium tetrahydride; In diethyl ether; Heating;

DOI:10.1021/jo00212a013

Reference yield:

2-(2,5-dichlorophenyl)acetonitrile (3218-50-6) → 2,5-dichloro-β-phenethyl alcohol (1875-87-2)

Guidance literature:

Multi-step reaction with 2 steps

1: 96 percent / H₂SO₄ / methanol / 72 h / Heating

2: 98.8 percent / LiAlH₄ / diethyl ether / Heating

With lithium aluminium tetrahydride; sulfuric acid; In methanol; diethyl ether;

DOI:10.1021/jo00212a013

Reference yield:

(2,5-dichloro-phenyl)-acetic acid butyl ester → 2,5-dichloro-β-phenethyl alcohol (1875-87-2)

Guidance literature:

With lithium aluminium tetrahydride; diethyl ether;

DOI:10.1021/jo01127a004

upstream raw materials:

methyl 2-(2,5-dichlorophenyl)acetate

2-(2,5-dichlorophenyl)acetonitrile

Downstream raw materials:

2,5-dichloro-β-phenethyl bromide

Refernces