Dimethyl oxazole-4,5-dicarboxy

Base Information

• Chemical Name: Dimethyl oxazole-4,5-dicarboxy
• CAS No.: 72030-81-0
• Molecular Formula: C₇H₇NO₅
• Molecular Weight: 185.136
• Mol file: 72030-81-0.mol

Synonyms:dimethyl oxazole-4,5-dicarboxylate

Chemical Property of Dimethyl oxazole-4,5-dicarboxy

Chemical Property:

• Melting Point: 74-76℃
• Boiling Point: 150℃/12mm

Purity/Quality:

99% ^*data from raw suppliers

DIMETHYL OXAZOLE-4,5-DICARBOXYLATE 95.00% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Uses: The teroxazole has been synthesized from dimethyl oxazole-4,5-dicarboxylate and lithiobenzyl isocyanide.

Technology Process of Dimethyl oxazole-4,5-dicarboxy

There total 3 articles about Dimethyl oxazole-4,5-dicarboxy which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

dimethyl dihydroxyfumarate (133-47-1) + formamide (77287-34-4,77287-35-5,60100-09-6) → dimethyl oxazole-4,5-dicarboxylate (72030-81-0)

Guidance literature:

With hydrogenchloride;

Reference yield:

monomethyl oxalyl chloride (5781-53-3) + isocyanoacetic acid methyl ester (39687-95-1) → dimethyl oxazole-4,5-dicarboxylate (72030-81-0)

Guidance literature:

Multistep reaction; (i) imidazole, Et₃N, THF, (ii) /BRN= 3537963/;

Reference yield:

→ dimethyl oxazole-4,5-dicarboxylate (72030-81-0)

Guidance literature:

Dihydromaleinsaeuredimethylester, Formamid;

DOI:10.1002/oms.1210111005

upstream raw materials:

monomethyl oxalyl chloride

isocyanoacetic acid methyl ester

dimethyl dihydroxyfumarate

formamide

Downstream raw materials:

oxazol

oxazole-4,5-dicarboxylic acid bis-benzylamide

N,N'-dibenzylethanediamide

4,4''-diphenyl-[5,4';5',5'']teroxazole