Coronarin D ethyl ether

Base Information

• Chemical Name: Coronarin D ethyl ether
• CAS No.: 138965-89-6
• Molecular Formula: C22H34O3
• Molecular Weight: 346.50400
• Mol file: 138965-89-6.mol

Synonyms:coronarin-D ethyl ether;coronarin B;

Chemical Property of Coronarin D ethyl ether

Chemical Property:

• PSA: 35.53000
• LogP: 5.41120

Purity/Quality:

98%min ^*data from raw suppliers

CoronarinDethylether >98%,StandardReferencesGrade ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of Coronarin D ethyl ether

There total 6 articles about Coronarin D ethyl ether which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 46.0%

ethanol (64-17-5) + coronarin D (119188-37-3) → coronarin-D ethyl ether (138965-89-6)

Guidance literature:

With toluene-4-sulfonic acid; In methanol; Reflux;

DOI:10.1016/j.ejmech.2019.04.023

Reference yield:

(3E)-3-{2-[(1S,4aS,8aS)-5,5,8a-trimethyl-2-methylidene-decahydronaphthalen-1-yl]ethylidene}oxolan-2-one (189239-51-8) → coronarin-D ethyl ether (138965-89-6)

Guidance literature:

Multi-step reaction with 3 steps

1: potassium hydroxide / tetrahydrofuran; ethanol / 20 °C

2: pyridinium chlorochromate / dichloromethane / 2 h / 20 °C

3: toluene-4-sulfonic acid / methanol / Reflux

With toluene-4-sulfonic acid; pyridinium chlorochromate; potassium hydroxide; In tetrahydrofuran; methanol; ethanol; dichloromethane;

DOI:10.1016/j.ejmech.2019.04.023

Reference yield:

(2E)-4-[(1S,4aS,8aS)-5,5,8a-trimethyl-2-methylidene-decahydronaphthalen-1-yl]-2-(2-hydroxyethyl)but-2-enoic acid → coronarin-D ethyl ether (138965-89-6)

Guidance literature:

Multi-step reaction with 2 steps

1: pyridinium chlorochromate / dichloromethane / 2 h / 20 °C

2: toluene-4-sulfonic acid / methanol / Reflux

With toluene-4-sulfonic acid; pyridinium chlorochromate; In methanol; dichloromethane;

DOI:10.1016/j.ejmech.2019.04.023

upstream raw materials:

(3E)-3-{2-[(1S,4aS,8aS)-5,5,8a-trimethyl-2-methylidene-decahydronaphthalen-1-yl]ethylidene}oxolan-2-one

ethanol

coronarin D

2-((1R,2R,4aS,8aS)-2-hydroxy-2,5,5,8a-tetramethyldecahydronaphthalen-1-yl)-N-methoxy-N-methylacetamide

Refernces