Cabraleahydroxylactone acetate

Base Information

• Chemical Name: Cabraleahydroxylactone acetate
• CAS No.: 35833-70-6
• Molecular Formula: C29H46O4
• Molecular Weight: 458.67
• Mol file: 35833-70-6.mol

Synonyms:Cabraleahydroxylactone acetate;Cabralea-hydroxylactone-3alpha-acetate;18-Norcholan-24-oic acid, 3-(acetyloxy)-20-hydroxy-4,4,8,14-tetramethyl-, γ-lactone, (3α,5α)-

Chemical Property of Cabraleahydroxylactone acetate

Chemical Property:

• Melting Point: 185 - 186 °C
• Boiling Point: 529.9±23.0 °C(Predicted)
• PSA: 52.60000
• Density: 1.09±0.1 g/cm3(Predicted)
• LogP: 6.69890

Purity/Quality:

98%min ^*data from raw suppliers

Cabraleahydroxylactoneacetate 95+% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of Cabraleahydroxylactone acetate

There total 6 articles about Cabraleahydroxylactone acetate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 73.0%

acetic anhydride (108-24-7) + 3β-hydroxy-17-[(5α-methyl)-3,4H-furane-2-one]-25,26,27-tris-nor-dammarane → 17-[(5α-methyl)-3,4H-furane-2-one]-3β-(O-acetyl)-25,26,27-tris-nor-dammarane (4726-64-1,17884-72-9,35833-70-6)

Guidance literature:

With pyridine; at 20 ℃; for 24h;

DOI:10.1039/d1ra04461c

Reference yield:

dipterocarpol (471-69-2) → 17-[(5α-methyl)-3,4H-furane-2-one]-3β-(O-acetyl)-25,26,27-tris-nor-dammarane (4726-64-1,17884-72-9,35833-70-6)

Guidance literature:

Multi-step reaction with 3 steps

1: chromium(VI) oxide; acetic acid / water / 5 - 20 °C

2: sodium tetrahydroborate; methanol / 0.33 h / 5 - 20 °C

3: pyridine / 24 h / 20 °C

With pyridine; chromium(VI) oxide; methanol; sodium tetrahydroborate; acetic acid; In water;

DOI:10.1039/d1ra04461c

Reference yield:

3β-acetoxy-20βFH-dammaran-20-ol (124580-50-3) → 17-[(5α-methyl)-3,4H-furane-2-one]-3β-(O-acetyl)-25,26,27-tris-nor-dammarane (4726-64-1,17884-72-9,35833-70-6)

Guidance literature:

With chromium(VI) oxide; acetic acid; benzene;

DOI:10.1039/jr9560002196

upstream raw materials:

3β-acetoxy-20β_FH-dammaran-20-ol

17-[(5α-methyl)-3,4H-furane-2-one]-25,26,27-trisnor-dammar-3-one

acetic anhydride

dipterocarpol

Refernces