1009036-29-6 Usage
General Description
7-Fluoroquinazolin-4-amine is a chemical compound with the molecular formula C8H6FN3. It is a derivative of quinazoline and contains a fluorine atom at the 7th position and an amine group at the 4th position of the quinazolin-4-one backbone. 7-Fluoroquinazolin-4-amine has potential applications in medicinal chemistry and pharmaceutical research, as it can be used as a building block for the synthesis of various organic compounds. It may also exhibit biological activity and could be explored for its potential as a drug candidate in the future. Additionally, 7-Fluoroquinazolin-4-amine may be used in the development of agrochemicals or other specialty chemicals, and its properties and reactivity make it a valuable intermediate in organic synthesis.
Check Digit Verification of cas no
The CAS Registry Mumber 1009036-29-6 includes 10 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 7 digits, 1,0,0,9,0,3 and 6 respectively; the second part has 2 digits, 2 and 9 respectively.
Calculate Digit Verification of CAS Registry Number 1009036-29:
(9*1)+(8*0)+(7*0)+(6*9)+(5*0)+(4*3)+(3*6)+(2*2)+(1*9)=106
106 % 10 = 6
So 1009036-29-6 is a valid CAS Registry Number.
1009036-29-6Relevant articles and documents
Discovery of novel aminoquinazolin-7-yl 6,7-dihydro-indol-4-ones as potent, selective inhibitors of heat shock protein 90
Huang, Kenneth H.,Barta, Thomas E.,Rice, John W.,Smith, Emilie D.,Ommen, Andy J.,Ma, Wei,Veal, James M.,Fadden, R. Patrick,Barabasz, Amy F.,Foley, Briana E.,Hughes, Philip F.,Hanson, Gunnar J.,Markworth, Christopher J.,Silinski, Melanie,Partridge, Jeffrey M.,Steed, Paul M.,Hall, Steven E.
scheme or table, p. 2550 - 2554 (2012/05/20)
A novel class of Hsp90 inhibitors, structurally distinct from previously reported scaffolds, was developed from rational design and optimization of a compound library screen hit. These aminoquinazoline derivatives, represented by compound 15 (SNX-6833) or 1-(2-amino-4-methylquinazolin-7-yl)-3,6,6-trimethyl-6, 7-dihydro-1H-indol-4(5H)-one, selectively bind to Hsp90 and inhibit its cellular activities at concentrations as low as single digit nanomolar.
