107583-03-9Relevant articles and documents
An unusual polyheterocyclic diversity by the π-cyclisation of N-carbamoyliminium ion, with or without tandem N,N-acetal cleavage, from spiro(imidazolidinoquinazolinones)
Pesquet, Anthony,Daich, Adam,Coste, Servane,Van Hijfte, Luc
, p. 1389 - 1396 (2008/12/21)
Spiro(imidazolidinoquinazolinones), obtained easily in one step from 1-carbamoylisatins, are readily converted in three steps by successive N-alkylations and sodium borohydride regio-selective reduction into the corresponding hydroxyspirolactams. The latt
Quinazolin-2-ones having a spirohydantoin ring. III. A general and efficient synthesis of 3'-substituted spiro[imidazolidine-4,4'(1'H)-quinazoline]-2,2',5(3'H)-triones
Yamagishi,Ozaki,Yamada,Da-Te,Okamura,Suzuki
, p. 1694 - 1698 (2007/10/02)
The reaction of 1-carbamoylisatins 2 with 2-ethyl-2-isothiourea hydrobromide in the presence of triethylamine followed by acid-catalyzed cyclization of the resulting 4-(2-ethyl-2-isothioureido)carbonyl-3,4-dihydro-4-hydroxy-2(1H)- quinazolinones provides