1188335-81-0Relevant articles and documents
3,3′-Disubstituted bipolar biphenyls as inhibitors of nuclear receptor coactivator binding
Weiser, Patrick T.,Williams, Anna B.,Hanson, Robert N.,Chang, Ching-Yi,McDonnell, Donald P.
, p. 6587 - 6590,4 (2012/12/12)
A series of bipolar biphenyl compounds was synthesized as proteomimetic analogs of the LXXLL penta-peptide motif responsible for the binding of coactivator proteins to the nuclear hormone receptor coactivator binding domain. These compounds were subjected
Synthesis of biphenyl proteomimetics as estrogen receptor-a coactivator binding inhibitors
Williams, Anna B.,Weiser, Patrick T.,Hanson, Robert N.,Guenther, Julian R.,Katzenellenbogen, John A.
supporting information; experimental part, p. 5370 - 5373 (2010/02/28)
"Chemical Equation Presented" A novel series of blphenyl proteomlmetic compounds were designed as estrogen receptor-α (ERα) coactivator binding Inhibitors. Synthesis was accomplished through a convergent approach, employing Suzuki coupling chemistry to li
