123171-59-5

Basic information

• Product Name: Cefepime hydrochloride
• Synonyms: Cefepim dihydrochloride;Pyrrolidinium, 1-[[(6R,7R)-7-[[(2Z)-(2-amino-4-thiazolyl)(methoxyimino)acetyl]amino]-2-carboxy-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-en-3-yl]methyl]-1-methyl-, chloride, monohydrochloride, monohydrate;Pyrrolidinium, 1-[[7-[[(2-amino-4-thiazolyl)(methoxyimino)acetyl]amino]-2-carboxy-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-en-3-yl]methyl]-1-methyl-, chloride, monohydrochloride, monohydrate, [6R-[6α,7β(Z)]]-;(6R,7R)-7-[(Z)-2-(2-Amino-4-thiazolyl)-2-(methoxyimino)acetamido]-3-[1-(1-methylpyrrolidinyl)methyl]-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-en-2-carboxylic acid hydrochloride monohydrate;Cefepime hydrochloride;CEFEPIME HYDROCHLORIDE (BUFFERED WITH ARGININE);1-[[(6R,7R)-7-[[(2Z)-(2-Amino-4-thiazolyl)(methoxyimino)acetyl]amino]-2-carboxy-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-en-3-yl]methyl]-1-methyl- pyrrolidinium Inner Salt Hydrochloride Monohydrate;Axepim
• CAS NO: 123171-59-5
• Molecular Formula: C19H24N6O5S2.2ClH.H2O
• Molecular Weight: 571.5
• EINECS: 1592732-453-0
• Product Categories: Heterocyclic Compounds;Heterocycles;Intermediates & Fine Chemicals;Pharmaceuticals;Sulfur & Selenium Compounds;Chiral Reagents
• Mol File: 123171-59-5.mol
• Article Data: 0

Chemical Properties

• Melting Point: 150°C (dec.)
• Appearance: white to faint yellow/
• Storage Temp.: Store at 0-5°C
• Solubility: Soluble in DMSO
• Sensitive: Light Sensitive
• CAS DataBase Reference: Cefepime hydrochloride(CAS DataBase Reference)
• NIST Chemistry Reference: Cefepime hydrochloride(123171-59-5)
• EPA Substance Registry System: Cefepime hydrochloride(123171-59-5)

Safety Data

• Hazard Codes: Xi
• Statements: 36/37/38-42/43
• Safety Statements: 22-26-36/37/39
• WGK Germany: 3
• Hazardous Substances Data: 123171-59-5(Hazardous Substances Data)

Usage

Description

Cefepime hydrochloride is a semisynthetic, fourth-generation cephalosporin antibiotic characterized by its white to pale yellow powder form. It is a hydrochloride that is the monohydrate of the dihydrochloride salt of cefepime, possessing potent antibacterial properties.

Uses

Used in Pharmaceutical Industry:
Cefepime hydrochloride is used as an antipsoriatic agent for its ability to alleviate the symptoms of psoriasis, a chronic skin condition characterized by red, scaly patches.
Used in Pharmaceutical Industry:
Cefepime hydrochloride is used as a protein synthesis inhibitor, functioning to disrupt the process of protein synthesis in bacteria, thereby inhibiting their growth and proliferation.
Used in Healthcare Industry:
Cefepime hydrochloride is used as a broad-spectrum antibiotic for its effectiveness against a wide variety of naturally antibiotic-resistant Gram-positive and Gram-negative bacteria. It is particularly notable for its resistance to hydrolysis by common plasmid and/or chromosomally-mediated β-lactamases, making it a valuable asset in the treatment of various bacterial infections.

InChI:InChI=1/C19H24N6O5S2.2ClH.H2O/c1-25(5-3-4-6-25)7-10-8-31-17-13(16(27)24(17)14(10)18(28)29)22-15(26)12(23-30-2)11-9-32-19(20)21-11;;;/h9,13,17H,3-8H2,1-2H3,(H3-,20,21,22,26,28,29);2*1H;1H2/b23-12-;;;/t13-,17-;;;/m1.../s1